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Our Research

The Heartburn Center is conducting cohort studies, clinical trials and comparative effectiveness research on cutting-edge therapies for GERD. Marcia Canto, M.D., director of the Heartburn Center and director of clinical research, Division of Gastroenterology, leads and oversees the research conducted at the Heartburn Center. A comprehensive, secure online registry facilitates clinical care and research at multiple practice locations.

Specific studies ongoing or planned:

  • Barrett’s esophagus
    • Endoscopic cryoballoon ablation
  • EndoFLIP
  • Eosinophilic Esophagitis
    • Medical versus endoscopic therapy
  • GERD in bariatric patients
  • Transoral incisionless fundoplication (TIF)
    • TIF Registry: a multicenter American prospective cohort aimed to assess short and long term outcomes of TIF/cTIF
    • Barrett’s esophagus patients with dysplasia following successful endoscopic ablation
    • Comparative outcomes of endoscopic versus surgical fundoplication
    • Laryngopharyngeal reflux disease (LPRD)
    • Post-POEM GERD
    • Rescue TIF after failed surgical fundoplication (Nissen, Toupet) or Stretta
    • TIF for proton pump inhibitor (PPI)-averse or -intolerant patients not interested in life-long medical therapy

If you are interested in more information about these studies, email