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Research Lab Results
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Adam D. Sylvester Lab
Research in the Adam D. Sylvester Lab primarily focuses on the way in which humans and primates... move through the environment, with the aim of reconstructing the locomotor repertoire of extinct hominins and other primates. We use a quantitative approach that involves the statistical analysis of three-dimensional biological shapes, specifically musculoskeletal structures, and then link the anatomy to function and function to locomotor behavior. view more
Research Areas: anatomy, biomechanics, locomotion, evolution, skeletal morphology -
Adam Sapirstein Lab
Lab WebsiteResearchers in the Adam Sapirstein Lab focus on the roles played by phospholipases A2 and their... lipid metabolites in brain injury. Using in vivo and in vitro models of stroke and excitotoxicity, the team is examining the roles of the cytosolic, Group V, and Group X PLA2s as well as the function of PLA2s in cerebrovascular regulation. Investigators have discovered that cPLA2 is necessary for the early electrophysiologic changes that happen in hippocampal CA1 neurons after exposure to N-methyl-d-aspartate (NMDA). This finding has critical ramifications in terms of the possible uses of selective cPLA2 inhibitors after acute neurologic injuries. view more
Research Areas: phospholipases A2, brain, stroke, lipid metabolites, excitotoxicity, brain injury, neurological disorders -
Adamo Cardiac Immunology Lab
Lab WebsiteOver the last few decades, a growing body of evidence has shown that the immune system is intim...ately connected with cardiac development, function and adaptation to injury. However, there is still much to learn and currently there are no immunomodulatory treatments to prevent or treat heart dysfunction.
Research Areas: heart disease, immunology, cardiac function and dysfunction
The Adamo Lab aims to study applied immunology in the context of cardiac function and dysfunction, to both elucidate fundamental properties of the immune systems and to develop novel therapeutic options for the rapidly growing number of patients living with heart disease.
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Adrian Dobs Lab
Researchers in the Adrian Dobs Lab study topics that include gonadal dysfunction, hyperlipidemi...a, diabetes mellitus, and the relationship between sex hormones and heart disease. We currently are investigating male gonadal function—with particular interest in new forms of male hormone replacement therapy—and hormonal changes related to aging. view more
Research Areas: diabetes mellitus, hormones, hyperlipidemia, male gonadal function, cardiovascular diseases, endocrinology -
Adult Cardiac Catheterization Laboratory
Our group is interested in the evaluation of basic pathophysiology in patients undergoing cardi...ac procedures, development and evaluation of new therapeutic strategies, and improving patient selection and outcomes following interventional procedures. view more
Research Areas: cardiac catheterization, Acute Myocardial Infarction -
Advanced Optics Lab
Lab WebsiteThe Advanced Optics Lab uses innovative optical tools, including laser-based nanotechnologies, ...to understand cell motility and the regulation of cell shape. We pioneered laser-based nanotechnologies, including optical tweezers, nanotracking, and laser-tracking microrheology. Applications range from physics, pharmaceutical delivery by phagocytosis (cell and tissue engineering), bacterial pathogens important in human disease and cell division.
Research Areas: optics, microscopy, physics, cellular biology, imaging, nanotechnology, drugs, tissue engineering
Other projects in the lab are related to microscopy, specifically combining fluorescence and electron microscopy to view images of the subcellular structure around proteins. view more -
Agrawal Lab
Lab WebsiteThe Agrawal Lab is focused on the medical and surgical treatment of otologic and neurotologic c...onditions. Research is focused on the vestibular system (the inner ear balance system), and how the function of the vestibular system changes with aging. Particular focus is given to study how age-related changes in vestibular function influence mobility disability and fall risk in older individuals. view more
Research Areas: cognition, visuospatial ability, vertigo, aging, balance, vestibular system -
Ahmet Gurakar Lab
The Ahmet Gurakar Lab is interested in bioartificial liver dialysis systems and the application... of total plasma exchange in the treatment of liver disorders. view more
Research Areas: transplants, viral hepatitis, liver diseases, plasma exchange -
Alan Baer Lab
Research in the Alan Baer Lab focuses on Sjogren's syndrome. Previously, we conducted the Sjogr...en's International Registry (SICCA), enrolling 300 patients and creating a valuable source of clinical data and biospecimens for research we're conducting with colleagues at Johns Hopkins and the University of California-San Francisco. Currently, we're conducting a longitudinal observational study of patients with Sjogren's syndrome. We're also collaborating with Dr. Ben Larman in the Department of Pathology, using phage immuno-precipation sequencing to work on a characterization of the complete autoantibody repertoire in Sjogren's syndrome patients. view more
Research Areas: autoantibodies, Sjogren's syndrome, autoimmune rheumatic diseases, observational data