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Assistant Professor, Interventional Neuroradiology
Dr. Pearl received her undergraduate degree in Mathematics from the University of North Carolina at Chapel Hill in 1998 and her Doctor of Medicine from Duke University in 2002. Following training in general surgery and diagnostic radiology at the George Washington University, she earned her certification from the American Board of Radiology in 2008. After completing fellowships in both Diagnostic Neuroradiology and Interventional Neuroradiology at the Johns Hopkins University, she joined the faculty at the Johns Hopkins University School of Medicine and the Johns Hopkins Hospital in 2010.
Her special areas of interest include the diagnosis and treatment of adult and pediatric neurovascular diseases, superficial vascular malformations including arteriovenous malformations (AVMs), venous malformations, and lymphatic malformations as well as radiation dose reduction strategies and innovative endovascular therapies for adult and pediatric tumors of the head, neck, and spine. She is the principal investigator for an active Phase II clinical trial involving the intra-arterial administration of chemotherapy for intraocular retinoblastoma. This study is enrolling patients now. She is also the principal investigator for a Phase I clinical trial involving the intra-arterial administration of chemotherapy for progressive diffuse intrinsic pontine gliomas. You can listen to an interview about this research on the American Journal of Neuroradiology Podcast.
In addition to being an Editor-in-Chief for the Journal of Pediatric Neuroradiology, she is also a member of the American Society of Neuroradiology, American College of Radiology, Senior Member of the Society of Neurointerventional Surgery, and a Diplomate of the American Board of Radiology with subspecialty board certification in Neuroradiology.
Dr. Pearl currently sees patients at the Johns Hopkins Hospital in her clinic by appointment.
Assistant Professor, Division of Interventional Neuroradiology, Department of Radiology. The Johns Hopkins Hospital and Johns Hopkins Bayview Medical Center, Baltimore, Maryland. July 2011 to present.
Director of Pediatric Neurointervention. Children’s National Medical Center. Washington, D.C. July 2011 to present.
Clinical Instructor, Division of Interventional Neuroradiology, Department of Radiology. The Johns Hopkins Hospital and Johns Hopkins Bayview Medical Center, Baltimore, Maryland. July 2010 to June 2011.
Education and Training
Fellowship, Interventional Neuroradiology, The Johns Hopkins University School of Medicine, Baltimore, MD.
Fellowship, Diagnostic Neuroradiology, The Johns Hopkins University School of Medicine, Baltimore, MD.
Residency, Diagnostic Radiology, The George Washington University School of Medicine, Washington, DC.
Internship, General Surgery, The George Washington University School of Medicine, Washington, DC.
Medical School, Duke University School of Medicine, Durham, NC.
Selected Recent Publications
1. Pearl, M. S., Torok, C., Wang, J., Wyse, E., Mahesh, M., & Gailloud, P. (2015). Practical techniques for reducing radiation exposure during cerebral angiography procedures. Journal of neurointerventional surgery, 7(2), 141-145.
3. Pearl, M. S., Roy, A., & Limb, C. J. (2014). High-resolution secondary reconstructions with the use of flat panel CT in the clinical assessment of patients with cochlear implants. American Journal of Neuroradiology, 35(6), 1202-1208.
Selected Honors and Recognition
2013, ASNR Foundation Scholar Award in Neuroradiology Research
You can listen to an interview about this award on the American Journal of Neuroradiology Podcast.
2012, Solving Kids' Cancer, Therapeutic Development Initiative Grant Award
2012, Children's National Medical Center, Children's Research Institute, Sheikh Zayed RAC Grant Award
2009, Codman and Shurtleff Inc. Fellowship Training Grant
2008, RSNA Roentgen Resident Research Award
2006, Society of Interventional Radiology, Resident-in-Training Scholarship
2001, Enhanced Research Training Program Grant, National Institutes of Health, National Institute of General Medical Sciences
1995, Intramural Research Training Award, National Institutes of Health, National Institutes of Environmental Health Sciences
Intra-arterial Chemotherapy for Retinoblastoma
The purpose of this Phase II clinical trial is to show that chemotherapy delivered directly to the eye is a safe and effective treatment alternative to systemic chemotherapy, radiation, and enucleation. More