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The Johns Hopkins School of Medicine Core Coins Program is a funding mechanism designed to encourage investigators to access core services and facilities. Our goal is to accelerate research by providing rapid, targeted funding to address small but critical gaps in basic, clinical and translational research work currently not funded by other sources. Core Coins will be awarded on a competitive basis to individual core facilities and subsequently to individual PIs via the awarded core. Core Coins will be administered through the iLab program through a distinct account provided to you after funds are awarded.
Core Coin Applicant Eligibility
School of Medicine Core facilities applying for funds must have adopted iLab Solutions or have signed up for implementation. For additional information about iLab Solutions, please contact either Shawn Franckowiak, Barbara Daily or Jeff Smith from the Office for Faculty Research Resources.
Funding and Timing
Core Coins will be awarded in amounts up to $25,000 per School of Medicine core facilities who have adopted iLab Solutions, our core management system, for services that are provided or have signed up for implementation. Core facilities will receive the funds directly and will be able to distribute the funds to investigators according to the criteria they describe in the application. Such criteria may include, but are not limited to: funding for junior faculty who have not yet established a significant funding base; faculty who need to generate preliminary data to strengthen a grant application; new faculty with specific needs for core facility resources to assist with the start-up of their laboratories; or projects involving cores that are newly established or are providing new services. All services proposed in RFAs must be available through iLab. Below examples of previously successful Core Coins Program applications along with their corresponding RFAs can be found. Work must be completed within 12 months of award date, and Core Coins are not renewable, transferrable or eligible for extension beyond 12 months.
Funds will not be allocated directly to the lab. They will be held in an account within iLab and used to subsidize usage fees for approved projects solicited by the core facility as needed. Each of the awarded core facilities will announce its own application process for Core Coins.
We are currently accepting applications for 2017 Core Coins through May 31, 2017 and funding will be announced by June 23, 2017. Please keep posted for further information about Core Coins 2018.
2017 Core Coin Awardees
- Computational Biology Consulting Core: To offer project support for exploratory projects involving deep sequencing of RNA (RNAseq) and metagenomic data analyses.
- Eukaryotic Tissue Culture Facility: For projects requiring specialized expertise and equipment required for culturing insect and mammalian cells for high-yield protein expression in suspension.
- Genetics Research Core Facility (GRCF): To offer specialized services for genomic analysis of single cells, including isolation of cells for capture, library preparation and deep sequencing RNA (RNAseq) with project design / data analysis.
- Mass Spectrometry and Proteomics Facility: To offer protein quantification and protein modification quantification services using isobaric mass tags and high-resolution mass analysis.
- Sidney Kimmel Comprehensive Cancer Center Analytical Pharmacology Shared Resource Core: To offer quantification of drugs and metabolites in biological fluids utilizing any of the four chromatographic (UPLC or UHPLC) instruments with a UV/Vis detector, triple stage quadruple mass spectrometer, and a Qtrap system with ion trap capabilities.
The Animal Behavioral Core: To offer comprehensive neurobehavioral phenotyping of untested animal models with various disease models and development of new behavioral assays.
2017 Core Coin Applications and RFAs
- Computational Biology Consulting Core: Application , RFA
- Eukaryotic Tissue Culture Facility: Application , RFA
- Genetics Research Core Facility (GRCF): Application , RFA
- Mass Spectrometry and Proteomics Facility: Application , RFA
- Sidney Kimmel Comprehensive Cancer Center Analytical Pharmacology Shared Resource Core: Application, RFA
- The Animal Behavioral Core: Application, RFA
Past Core Coin Awardees
- Center for Proteomics Discovery: To offer comprehensive profiling of post-translational modifications, quantitative analysis of proteomes, and top-down and middle-down proteomics services.
- Genetics Resources Core Facility: For projects utilizing the novel 10x Genomic Single Cell Platform for the isolation of cells from four treatment groups (a maximal 24,000 cells) and downstream RNAseq (100,000 reads per cell), or the utilization of the new Fluidigm C1 for 4 treatment groups (a maximal 384 cells) and downstream RNAseq (100,000 reads per cell).
- Mass Spectrometry and Proteomics Facility: To offer protein quantification and protein modification quantification services using isobaric mass tags as part of this RFA. These services will be offered for global quantitative proteomic experiments as well as quantitative experiments focusing on a specific protein or the protein’s modifications.
- Sidney Kimmel Cancer Center Flow Cytometry and Immune Monitoring Core: For projects to receive approximately five hours of cell sorting on the BD Influx or one FLUOROSPOT assay.
Past Core Coin Core Applications and RFAs
- Center for Proteomic Discovery: Application and RFA
- Genetic Resources Core Facility - Application and RFA
- Mass Spectrometry and Proteomics Facility - Application and RFA
- Sidney Kimmel Cancer Center Flow Cytometry an Immune Monitoring Core - and
Instrumentation grants are reviewed centrally by the Johns Hopkins University Research Administration, Research Development - Limited Submissions Programs office. Please contact firstname.lastname@example.org with inquiries.