Principal Investigator:
Wei Dong Gao, M.B., M.D., Ph.D., M.S.
Department:
Anesthesiology and Critical Care Medicine
Work in the Wei Dong Gao Lab primarily focuses on heart failure and defining molecular and cellular mechanisms of contractile dysfunction. We use molecular biology and proteomic techniques to investigate the changes that myofilament proteins undergo during heart failure and under drug therapy. We're working to determine the molecular nature of nitroxyl (HNO) modification of tropomyosin.
Research Areas: heart disease, contractile dysfunction, heart failure, cardiovascular diseases, molecular biology