Principal Investigator:
Robert Brodsky, M.D.
Department:
Medicine
Investigators in the Robert Brodsky Lab study normal and abnormal hematopoiesis, particularly mutations of the phosphatidylinositol glycan anchor biosynthesis class A (PIG-A) gene in aplastic anemia. Our team has developed a new diagnostic assay for paroxysmal nocturnal hemoglobinuria (PNH) that is based on the toxin Aaeromonas hydrophila.
Research Areas: high-dose cyclophosphamide, hematopoiesis, paroxysmal nocturnal hemoglobinuria, aplastic anemia