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  • Stephen Mathai Lab

    The Stephen Mathai Lab focuses its research on pulmonary medicine. We're particularly interested in scleroderma-associated pulmonary hypertension, pulmonary complications of connective tissue disease, idiopathic pulmonary fibrosis and pulmonary hypertension.

    Principal Investigator

    Stephen Carl Mathai, M.D., M.H.S.

    Department

    Medicine

  • Henry Fessler Lab

    Research in the Henry Fessler Lab is focused on pulmonary medicine. We are interested in heart-lung interaction, mechanical ventilation and lung mechanics. We’re also interested in medical education and recently examined contemporary strategies for effective lecturing.

    Principal Investigator

    Henry Eric Fessler, M.D.

    Department

    Medicine

  • Eric McCollum Lab

    Research in the Eric McCollum Lab focuses on pediatric pulmonary medicine, particularly pulmonary diseases among children in undeveloped, low-resource countries. We are taking part in the IMPACT trial, which looks at the impact of bubble continuous positive airway pressure (bCPAP) on the mortality of Malawian children with pneumonia.

    Principal Investigator

    Eric Douglass McCollum, M.D., M.P.H.

    Department

    Pediatrics

  • Sean Agbor-Enoh Lab

    Research in the Sean Agbor-Enoh Lab explores topics within the field of pulmonary medicine. Our team also participates in clinical trials that explore new techniques for diagnosing rejection following an organ transplant. One current study is seeking to develop a new blood test that may be used instead of biopsies to diagnose rejection after transplant.

    Principal Investigator

    Sean Agbor-Enoh, M.D., Ph.D.

    Department

    Medicine

  • Outcomes After Critical Illness and Surgery Group

    The Outcomes After Critical Illness and Surgery Group is focused on understanding and improving patient outcomes after critical illness and surgery. Research projects include improving long-term outcomes research for acute respiratory distress syndrome/acute respiratory failure (ARDS/ARF) patients; examining the long-term outcomes for acute lung injury/acute respiratory distress syndrome (ALI/ARDS) patients; and evaluating the effects of lower tidal volume ventilation and other aspects of critical illness and ICU care on the long-term physical and mental health outcomes of ALI/ARDS patients.
    Lab Website

    Principal Investigator

    Dale M Needham, M.D., Ph.D.

    Department

    Medicine

  • Charles Wiener Lab

    The Charles Wiener Lab primarily conducts research on pulmonary circulation and hypoxia as well as respiratory muscle function in patients with neuromuscular diseases. Our recent studies have included investigating the treatment of pericardial effusions in patients with pulmonary arterial hypertension and examining the use of non-invasive ventilation in patients with amyotrophic lateral sclerosis (ALS). We also have an interest in medical education research. Our work in this area has included reviewing the role of academic medical centers in emerging health care markets.

    Principal Investigator

    Charles Wiener, M.D.

    Department

    Medicine

  • Charles Wiener Lab

    The Charles Wiener Lab primarily conducts research on pulmonary circulation and hypoxia as well as respiratory muscle function in patients with neuromuscular diseases. Our recent studies have included investigating the treatment of pericardial effusions in patients with pulmonary arterial hypertension and examining the use of non-invasive ventilation in patients with amyotrophic lateral sclerosis (ALS). We also have an interest in medical education research. Our work in this area has included reviewing the role of academic medical centers in emerging health care markets.

    Principal Investigator

    Charles Wiener, M.D.

    Department

    Medicine

  • Shyam Sundar Biswal Lab

    xResearch in the Shyam Biswal Lab focuses on therapeutic resistance of cancer due to a gain-of-function mutation in transcription factor Nrf2. Using patient-derived xenografts in humanized immunocompetent mice and GEM models, we aim to understand the mechanisms of oncogenic cooperation and metabolic adaptation in cancer cells. We’re also investigating the systemic and pulmonary effects of air pollution as well as the health effects of recent tobacco products, such as electronic cigarettes and water pipes.

    Principal Investigator

    Shyam Sundar Biswal, Ph.D.

    Department

    Medicine

  • Robert Wise Lab

    The Robert Wise Lab conducts clinical trials to study chronic obstructive lung diseases (COPD). We investigate inhaled corticosteroids in patients with mild to moderate COPD and the effectiveness of anti-inflammatories in allowing lung growth in mild to moderate asthmatic children. Our research includes exploring the efficacy of various treatments for asthmatic women who are pregnant and of lung-volume reduction surgery for emphysema patients. We also conduct studies of the clinical epidemiology, pathobiology and treatment of interstitial lung disease in patients with scleroderma.

    Principal Investigator

    Robert A Wise, M.D.

    Department

    Medicine

  • Noah Lechtzin Lab

    Research in the Noah Lechtzin Lab investigates several important aspects of cystic fibrosis (CF), including the impact of antibiotic-resistant bacterial infections in CF patients and new therapy options for individuals with CF. Our research into new CF therapies has included studies on home electronic symptom and lung function monitoring, transbronchial needle aspiration and bedside percutaneous endoscopic gastrostomy tube placement. We also explore the role of metabolic complications in CF patients by examining how the disease is impacted by factors such as vitamin D deficiency, osteoporosis and testosterone deficiency.

    Principal Investigator

    Noah Lechtzin, M.D., M.H.S.

    Department

    Medicine