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Fundamentals (logo) Fundamentals April 2021

Stories on basic, fundamental research at Johns Hopkins Medicine. Sponsored by the Institute for Basic Biomedical Sciences.

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Featured Story For mRNA Vaccines, COVID-19 Is Just the Beginning

Easy to manufacture and update, these new vaccines may be a powerful tool against emerging variants and other infectious diseases.

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An illustration of COVID-19 vaccines. A tray of blue test tubes sits behind a white vial labeled COVID-19 coronavirus vaccine and a vaccination needle with a green tip all against a blue background.

Articles in this Issue

  • Image of the Month: ‘Cilia’ Little Fingers

    Cilia are tiny fingerlike protrusions that sweep away debris and mucus. In these 3D images of epithelial cells in a mouse’s trachea, scientist and Johns Hopkins University President’s Frontier Award winner Andrew Holland, and Ph.D. candidate Gina LoMastro, demonstrate how cells build cilia.

    a microscope image showing red, elongated structures, which are cilia

  • Video of the Month: Nanodrugs Assemble

    Getting therapeutics to slip inside a tumor cell is tricky business.

    Microscope image of small lime green dots surrounding larger roughly spherical blue shapes. The green dots in this image are the nanodrugs that have entered human colon cancer cells and moved toward blue-dyed nuclei.
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