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Current News Releases - 2018

Current News Releases

Released: July 18, 2018

An analysis of more than 1,000 people with and without psychiatric disorders has shown that nitrates—chemicals used to cure meats such as beef jerky, salami, hot dogs and other processed meat snacks—may contribute to mania, an abnormal mood state. Mania is characterized by hyperactivity, euphoria and insomnia.

Released: July 17, 2018

Less education and unaccompanied medical visits linked to lack of formal diagnosis or awareness of diagnosis

A Johns Hopkins Medicine analysis of information gathered for an ongoing and federally sponsored study of aging and disability adds to evidence that a substantial majority of older adults with probable dementia in the United States have never been professionally diagnosed or are unaware they have been.

Released: July 12, 2018

In a “proof of concept” study, scientists at Johns Hopkins Medicine say they have successfully delivered nano-size packets of genetic code called microRNAs to treat human brain tumors implanted in mice. The contents of the super-small containers were designed to target cancer stem cells, a kind of cellular “seed” that produces countless progeny and is a relentless barrier to ridding the brain of malignant cells.

Released: July 11, 2018

The gains in insurance coverage with the Patient Protection and Affordable Care Act (ACA) have already translated into improved health for young women with gynecologic cancers, who are getting diagnosed at earlier stages of their disease because of ACA benefits. That’s the conclusion of a new study by researchers at Johns Hopkins Medicine, who looked at nationwide trends in gynecologic cancer diagnosis in a large population of women before and after the ACA’s implementation in 2010.

Released: July 10, 2018

Johns Hopkins researchers have found that the cellular “garbage disposal,” known to scientists as proteasomes, may not only be responsible for the removal of cellular waste, but actually work on some of the most important proteins to neuronal development.

Released: July 9, 2018

Small Study Based on Subjective Interviews Explores Decision-Making Process in Life-and-Death Emergencies

In a small study based on conversations with 20 hospital-based surgeons, Johns Hopkins researchers say they found that most report feeling pressure to operate under severe emergency situations, even when they believe the patients would not benefit.
Released: July 2, 2018

Researchers at Johns Hopkins have added to evidence that rising and chronic inflammation as measured by a biomarker in the blood in middle and late age are linked to visible structural changes in the brains of people with poor cognition and dementia.
Released: July 2, 2018

Johns Hopkins researchers say they have developed an experimental drug, similar to compounds used to treat diabetes, that slows the progression of Parkinson’s disease itself — as well as its symptoms — in mice
Released: July 2, 2018

New methods of studying the evolution of treatment resistance in head and neck cancer are being developed by researchers at the Johns Hopkins Kimmel Cancer Center.
Released: June 29, 2018

Recognized for commitment to nursing excellence for fourth time

Baltimore (June 29, 2018) — The Johns Hopkins Hospital has once again achieved Magnet designation in recognition of its nursing excellence. The American Nurses Credentialing Center’s Magnet Recognition Program is the highest national credential for professionalnursing practice. Only about 7.5 percent of U.S. health care organizations have achieved Magnet recognition.
Released: June 26, 2018

BALTIMORE (June 26, 2018) – Johns Hopkins Children’s Center ranked #8 in the nation on U.S. News & World Report’s 2018-19 Best Children’s Hospitals Honor Roll. Johns Hopkins Children’s Center has the distinction of being the only children’s hospital integrated with an adult facility to make the Honor Roll this year.
Released: June 25, 2018

Proof-of-concept study in mice and rats focuses on new target for opioid drugs

A team of researchers at Johns Hopkins have found that activating nerve cell receptors along two chemical pathways — one that has previously been linked to how the brain senses “itch” — may improve pain relief when combined with conventional ways to blunt pain using opioid drugs, such as morphine. 
Released: June 25, 2018

Researchers at the Johns Hopkins Kimmel Cancer Center and the Bloomberg~Kimmel Institute for Cancer Immunotherapy (BKI) released a study investigating the use of combination checkpoint immunotherapy in the treatment of a lethal form of advanced prostate cancer. The study suggested a genetic subset of prostate cancer may benefit from this form of immunotherapy.
Released: June 22, 2018

A gathering of clinicians, researchers, advocates and patients will share information and shed light on the need for improved focus and funding for metastatic and stage IV breast cancer.

The fifth annual Metastatic Breast Cancer Conference invites participants from around the world to discuss ongoing research, showcase new ideas from young scientists, and bring together advocates who are working with metastatic breast cancer patients. This year, the conference will be hosted by the Johns Hopkins Kimmel Cancer Center and the Johns Hopkins School of Medicine in Baltimore on Nov. 15 and 16.
Released: June 19, 2018

Reviewing medical information gathered on more than 6,000 adults over a 10-year period, Johns Hopkins researchers have found that lower than normal blood levels of vitamin D were linked to increased risk of early signs of interstitial lung disease (ILD).
Released: June 18, 2018

J. Alex Haller Jr., M.D., a trailblazing pioneer in pediatric surgery, pediatric trauma treatment and biomedical ethics who transformed the practice of pediatric care at Johns Hopkins and throughout the nation, died on June 13 in Glencoe, Maryland. He was 91.
Released: June 14, 2018

Josie the dog is first to complete clinical trial for deadly dog cancer

At 12 years old (84 in dog years), the Robertson family’s beloved terrier mix, Josie, had been through it all. She had a tattoo of the phone number from the “last chance” shelter where her family rescued her, she had had both knees repaired, was injured when a bigger dog attacked her, and was losing her sight and hearing with age — all before she was diagnosed with one of the deadliest cancers known to dogkind, hemangiosarcoma.
Released: June 14, 2018

Johns Hopkins scientists advance knowledge of prurigo nodularis

An international team led by Johns Hopkins Medicine researchers has conducted what is believed to be the largest detailed published study of people with a poorly understood skin condition known as prurigo nodularis (PN). Such studies collect information on a whole subset of people at once and at a particular point in time.
Released: June 14, 2018

Working with hundreds of time-lapse videos of mouse tissue, a team of biologists joined up with civil engineers to create what is believed to be the first 3D computer model to show precisely how the tiny tubes that funnel milk through the breasts of mammals form.
Released: June 13, 2018

In a small study of ambulatory surgical centers across the country, Johns Hopkins quality care researchers found that publicly listing the prices of common operations, such as uncomplicated labor and delivery and tonsillectomies, generally increased business, revenue and patient satisfaction.
Released: June 12, 2018

Erectile dysfunction (ED) indicates greater cardiovascular risk, regardless of other risk factors, such as cholesterol, smoking and high blood pressure, according new research published in the American Heart Association’s journal Circulation.
Released: June 11, 2018

Researchers with the Johns Hopkins Kimmel Cancer Center and the Johns Hopkins University School of Medicine received a $3 million grant to use computational modeling and software to understand biological data, in combination with unique in vitro and animal studies, to better treat liver cancer.
Released: June 7, 2018

The Johns Hopkins Kimmel Cancer Center and more than 70 National Cancer Center-designated cancer centers across the country endorsed the goal of eliminating cancers caused by the human papillomavirus (HPV) with the use of gender-neutral HPV vaccination and evidence-based cancer screening in an open letter to patients and medical providers.
Released: June 7, 2018

By screening 250 user reviews and comments for a once popular -- but proven inaccurate -- mobile app claiming to change your iPhone into a blood pressure monitor, Johns Hopkins researchers have added to evidence that a high “star rating” doesn’t necessarily reflect medical accuracy or value.
Released: June 6, 2018

Yesterday the American Society of Regional Anesthesia and Pain Medicine, the American Academy of Pain Medicine and the American Society of Anesthesiologists published new consensus guidelines on the use of IV ketamine infusions for chronic and acute pain management. The new guidelines were published in Regional Anesthesia and Pain Medicine.

Released: June 5, 2018

Acidosis related to use of metformin seen only in those with severely decreased kidney function

Results of a large-scale study suggest that the oral diabetes drug metformin is safe for most diabetics who also have chronic kidney disease (CKD). The study of more than 150,000 adults by Johns Hopkins Medicine investigators found that metformin’s association with the development of a life-threatening condition called lactic acidosis was seen only among patients with severely decreased kidney function.
Released: June 1, 2018

Agricultural antibiotics are responsible for roughly 20 percent of resistant infections in humans according to the Centers for Disease Control and Prevention, however, its urgency as a public health concern has been understated. Martin Makary, M.D., M.P.H., a professor of surgery at the Johns Hopkins University School of Medicine, insists that doctors start leading the way for antibiotic-free foods in the same way they advocate for smoking cessation.

Released: May 31, 2018

Johns Hopkins study finds some outpatient centers have infection risks 100 times higher than expected

The rates of infection following colonoscopies and upper-GI endoscopies performed at U.S. outpatient specialty centers are far higher than previously believed, according to a Johns Hopkins study published online this month in the journal Gut.
Released: May 30, 2018

The American Society of Clinical Oncology Annual Meeting brings together more than 32,000 oncology professionals from around the world to discuss state-of-the-art treatment modalities, new therapies, and ongoing controversies in the field.
Released: May 29, 2018

The 16 awardees from The Johns Hopkins University — representing research ranging from basic sciences to clinical sciences — are among 25 scientists who will share the $7.1 million award approved by The Maryland Stem Cell Research Commission.

Released: May 29, 2018

Results of a study of nearly 2,000 U.S. citizen children and their mothers add to growing evidence of the multigenerational, beneficial effects of the Deferred Action for Childhood Arrivals (DACA) immigration policy on children who are citizens, illustrating increased participation in the Special Supplemental Nutrition Program for Women, Infants and Children (WIC) among citizen children whose mothers are likely eligible for DACA.
Released: May 29, 2018

Findings may provide new insights into the connections between movement and touch

Scientists report they have uncovered a previously overlooked connection between neurons in two distinct areas of the mammalian brain. The neurons, they say, control the sense of touch, and their experiments in mice offer insights into mapping brain circuitry that is responsible for normal and abnormal perception and movements linked to touch.
Released: May 29, 2018

In an analysis of data collected from more than 2,800 women after menopause, Johns Hopkins researchers report new evidence that a higher proportion of male to female sex hormones was associated with a significant increased relative cardiovascular disease risk.
Released: May 24, 2018

A study of more than 7,000 low-income, urban mothers enrolled in the Boston Birth Cohort found that fewer than 5 percent of them started folic acid supplementation and used it almost daily before pregnancy, a widely recommended public health measure designed to prevent potentially crippling birth defects.

Released: May 18, 2018

A project in the radiation oncology outpatient unit at Johns Hopkins Hospital showed an improvement in clinician’s comfort level in responding to urgent patient care situations after a department-wide exercise focused on recognizing the signs when a patient’s condition was declining during their appointments.

Released: May 17, 2018

A small study of adults with the most common form of pancreatic cancer adds to evidence that patients with BRCA1 or BRCA2 gene mutations long linked to a high risk of breast cancer have poorer overall survival rates than those without the mutations.

Released: May 15, 2018

Burn expert joining the multidisciplinary team to advance burn care research and future discoveries

C. Scott Hultman, M.D., M.B.A., F.A.C.S., has joined the Department of Plastic Surgery as the new director of the Johns Hopkins Burn Center. He also will join the faculty at Johns Hopkins University School of Medicine as a professor of plastic and reconstructive surgery.
Released: May 15, 2018

Scientists at Johns Hopkins Medicine and the National Tsing Hua University in Taiwan say they have found a fast way to manipulate a cell’s cilia, the tiny, fingerlike protrusions that “feel” and sense their microscopic environment. The experiments, performed in mouse cells, may advance scientists’ efforts to not only understand how the nanosized antennae work, but also how to repair them.

Released: May 15, 2018

Lorem Therapeutics will use support to enhance drug discovery efforts around critical cancer indications

The Johns Hopkins University announces that IP Group has funded the creation of Lorem Therapeutics as part of an ongoing collaboration between the university and the intellectual property commercialization company to explore, identify and commercialize technologies. Lorem will be focused on developing early-stage therapeutics, bridging the gap from drug discovery to investigative new drug (IND) status, specifically novel small molecule prodrugs for cancer indications.

Released: May 15, 2018

By analyzing reported physical activity levels over time in more than 11,000 American adults, Johns Hopkins Medicine researchers conclude that increasing physical activity to recommended levels over as few as six years in middle age is associated with a significantly decreased risk of heart failure, a condition that affects an estimated 5 million to 6 million Americans.

Released: May 14, 2018

The High Value Practice Academic Alliance (HVPAA), led by Johns Hopkins Medicine, has collaborated with the Health Research and Educational Trust (HRET), the research, education and implementation science affiliate of the American Hospital Association (AHA), to host and direct the HVPAA’s annual High Value Health Care Conference on Sept. 21-23 at the Baltimore Convention Center.
Released: May 14, 2018

The annual meeting of the Society for Academic Emergency Medicine (SAEM). The SAEM 2018 meeting will bring together more than 3,000 physicians, researchers, residents and medical students from around the world.
Released: May 14, 2018

The Johns Hopkins Rehabilitation Network is opening a new therapy clinic inside the acac Fitness & Wellness center in Timonium, Maryland. This model of business is becoming an increasingly popular way for health clubs and health systems to approach delivery of care, providing access to club members as well as patients in a community setting.

Released: May 14, 2018

Georgios Margonis, M.D., Ph.D., a surgical oncology fellow at the Johns Hopkins University School of Medicine, and Matthew Weiss, M.D., surgical director of the Johns Hopkins Liver and Pancreas Cancer Multidisciplinary Clinics, report advances in efforts to improve the treatment and prognosis of colorectal cancers that have spread to the liver.

Released: May 9, 2018

A Johns Hopkins study found that physicians who use stigmatizing language in their patients’ medical records may affect the care those patients get for years to come.

Released: May 9, 2018

A Johns Hopkins breast cancer doctor will be honored by the Baltimore Orioles as a Birdland Community Hero at the team’s Mother’s Day game at Oriole Park at Camden Yards.
Released: May 9, 2018

Protein clumping may contribute to heart failure development and could be used as a diagnostic tool for testing therapies or disease progression

Similar to how protein clumps build up in the brain in people with some neurodegenerative diseases such as Alzheimer’s and Parkinson’s diseases, protein clumps appear to accumulate in the diseased hearts of mice and people with heart failure, according to a team led by Johns Hopkins University researchers.

Released: May 8, 2018

Every year since 2008, the Johns Hopkins Center for Women’s Health, Sex, and Gender Research (formerly the Johns Hopkins Women’s Health Research Group) has hosted the Women’s Health Research Symposium to showcase research collaborations across Johns Hopkins’ schools of medicine, public health and nursing.
Released: May 8, 2018

Nancy Schoenborn, M.D., assistant professor in the Department of Geriatric Medicine and Gerontology at the Johns Hopkins University School of Medicine, and colleagues went straight to the source and conducted three qualitative studies that put older adults at the forefront in order to gain a better understanding of if, and how, they prefer to discuss various health topics.

Released: May 3, 2018

The annual meeting of the Pediatric Academic Societies (PAS), which consists of The American Pediatric Society, the Society for Pediatric Research, the Academic Pediatric Association and the American Academy of Pediatrics. The PAS 2018 Meeting will bring together more than 8,000 pediatricians, research scientists, health care providers and policymakers from around the world.

Released: May 3, 2018

In studies with monkeys, Johns Hopkins researchers report that they have uncovered significant new details about how the cerebellum — the “learning machine” of the mammalian brain — makes predictions and learns from its mistakes, helping us execute complex motor actions such as accurately shooting a basketball into a net or focusing your eyes on an object across the room.
Released: May 1, 2018

When a new park is built, a tax is instituted on fast food or a ban put in place against soft drinks in a school, public health researchers must often rely on “after the fact” observational studies to evaluate the impact of such efforts on rates of obesity in a particular population and try to clearly identify and measure the factors that worked or didn’t.

Released: April 30, 2018

Patients also improperly store and dispose of opioids

A new study led by Johns Hopkins researchers adds to growing evidence that patients underuse nonopioid pain relievers to supplement opioid pain management after spine and joint surgery.
Released: April 26, 2018

A study of nearly 6,000 Americans followed for 24 years from middle to late adulthood found that having chronic inflammation in middle age may be linked to an increased risk of frailty and overall poorer health decades later.

Released: April 26, 2018

Johns Hopkins researchers report success with a smart phone video-based app that substitutes for a daily in-person visit by a health care worker required for tuberculosis treatment known as directly observed therapy, or DOT. The preliminary study showed that the app may be less costly and may improve privacy concerns raised by patients compared to in-person visits.

Released: April 25, 2018

Bedtimes are much later on weekends, especially for teens

A new analysis by Johns Hopkins researchers of national data gathered from physical activity monitors concludes that most Americans hit the sack later on Friday, Saturday and Sunday nights. Delayed bedtimes are especially pronounced for teens and young adults.

Released: April 23, 2018

Many soldiers returning from combat bear visible scars, or even lost limbs, caused by blasts from improvised explosive devices, or IEDs. However, some servicemen also return with debilitating hidden injuries — the loss of all or part of their genitals. Now, the Johns Hopkins reconstructive surgery team that performed the country’s first bilateral arm transplant in a wounded warrior has successfully performed the first total penis and scrotum transplant in the world.

Released: April 23, 2018

Event takes place at the Shops at Kenilworth

Make room in your closet for some fabulous gently used designer and vintage clothing from the Spring Best Dressed Sale, a fundraising project of The Women’s Board of The Johns Hopkins Hospital. The sale takes place from 9 a.m. to 6 p.m. Friday, May 11, and 10 a.m. to 2 p.m. Saturday, May 12, on the upper level of The Shops at Kenilworth, 800 Kenilworth Drive, Towson.
Released: April 20, 2018

Often people think performing in front of others will make them mess up, but a new study led by a Johns Hopkins University neuroscientist found the opposite: being watched makes people do better.

Released: April 19, 2018

Five Johns Hopkins scientists, with specialties spanning computation, genetics, statistics and engineering, are among 83 others from 53 institutions in the U.S and eight other countries, who will share in a $15 million award from the Chan Zuckerberg Initiative.

Released: April 19, 2018

Johns Hopkins scientist Steven Salzberg, Ph.D., known for his ability to tackle the most difficult projects in genome sequencing, has been elected as a member of the American Academy of Arts and Sciences. He joins the group of 213 scientists, scholars, writers, artists and other leaders, including former President Barack Obama and Supreme Court Justice Sonia Sotomayor, who make up the class of 2018.

Released: April 18, 2018

In a new analysis of interviews conducted with children who have asthma, their caregivers and their clinicians, Johns Hopkins researchers found that there was significant lack of agreement about why the kids miss their needed daily anti-inflammatory medication.

Released: April 18, 2018

Using computer models and laboratory rats, Johns Hopkins researchers have demonstrated that “direct electrical current” can be delivered to nerves preferentially, blocking pain signals while leaving other sensations undisturbed.

Released: April 16, 2018

A drug given to early stage lung cancer patients before they undergo surgery showed major tumor responses in the removed tumor and an increase in anti-tumor T-cells that remained after the tumor was removed, which resulted in fewer relapse cases in the patients.

Released: April 16, 2018

A new Johns Hopkins Medicine analysis of national trauma data shows that trauma patients were four times more likely to die from gunshot wounds and nearly nine times more likely to die from stab wounds before getting to a trauma center in 2014, compared with rates in 2007.

Released: April 16, 2018

In a multicenter database study of adults who had undergone surgery for spinal deformities, researchers say that those who had used narcotics daily on average had worse outcomes, such as longer intensive care unit stays and more severe postop disability, compared with those who did not use opioids preoperatively.

Released: April 12, 2018

The Johns Hopkins Center for Dynamic Health is hosting a symposium on the science of exercise as medicine. This inaugural event will feature talks from leading experts from Johns Hopkins Medicine, Johns Hopkins Bloomberg School of Public Health and other neighboring institutions. The symposium will discuss research about physical activity and exercise as well as clinical activities.  

Released: April 10, 2018

Adding the monoclonal antibody drug trastuzumab—already used to treat certain breast cancers—to the chemotherapy regimen of women with a rare form of uterine cancer lengthens the amount of time their tumors are kept from growing, according to Johns Hopkins Medicine researchers conducting a small phase II trial of the regimen, testing its safety and value.

Released: April 5, 2018

In a review article published April 5 in the New England Journal of Medicine, scientist Andrew Feinberg, M.D., calls for more integration between two fields of DNA-based research: genetics and epigenetics.

Released: April 5, 2018

In a mouse study, a drug that has helped millions of people around the world manage their diabetes might also help people ready to kick their nicotine habits.

Released: April 2, 2018

In the tiny brain space where two nerve cells meet, chemical and electric signals shuttle back and forth, a messaging system that ebbs and flows in those synaptic spaces, sometimes in ways that scientists believe aid and abet learning and memory. But because most of the proteins found in those synapses die and renew themselves so rapidly, scientists have had a hard time pinning down how synapses are stable enough to explain the kind of learning and memory that lasts a lifetime. 

Released: April 2, 2018

As part of the Maryland Trauma System distracted driving awareness statewide initiative for Distracted Driving Awareness Month, some Johns Hopkins Health System trauma centers will host events to educate people about the dangers of distracted driving. The events are free and open to the public.

Released: March 29, 2018

As part of a statewide campaign, Johns Hopkins leadership, clinicians, families of donors and recipients to raise ‘Donate Life’ flag to honor organ, eye and tissue donors

Throughout the month of April, in celebration of National Donate Life Month, The Johns Hopkins Hospital will fly the Donate Life flag to show solidarity for the importance of organ donation.


Released: March 28, 2018

By modifying a muscle transplant operation, Johns Hopkins surgeons report they are able to restore authentic facial expressions of joy¾wide and even smiles¾to selected patients with one-sided facial muscle paralysis due to birth defects, stroke, tumors or Bell’s palsy.  

Released: March 27, 2018

Working with cells that line the innermost layer of the blood vessels, Johns Hopkins investigators say they have made a leap forward in understanding the underlying biology behind pulmonary hypertension, a dangerous type of high blood pressure in lungs that ultimately leads to right heart failure and death.

Released: March 26, 2018

By combining high-tech 3-D printing technology with everyday items such as a kickball and pieces of chicken breast, surgeons at Johns Hopkins report they have devised an innovative way to “rehearse” a complex minimally invasive surgical repair of open lesions on fetal spinal cords inside the womb.

Released: March 22, 2018

Researchers at The Johns Hopkins Kimmel Cancer Center have developed a test for urine, gathered during a routine procedure, to detect DNA mutations identified with urothelial cancers.

Released: March 22, 2018

Cervical fluid samples gathered during routine Papanicolaou (Pap) tests are the basis of a new screening test for endometrial and ovarian cancers developed by researchers at the Johns Hopkins Kimmel Cancer Center.
Released: March 21, 2018

A Johns Hopkins-led study suggests HIV testing in a South African emergency department is an effective strategy to identify patients missed by current testing initiatives

South Africa has the worst epidemic of HIV in the world. According to the Joint United Nations Programme on HIV/AIDS, 19 percent of the global number of people living with HIV are in South Africa. Many people in South Africa and around the globe do not even know they have HIV.

Released: March 20, 2018

Limiting first-year medical residents to 16-hour work shifts, compared to “flexing” them to allow for some longer shifts, generally makes residents more satisfied with their training and work-life balance, but their training directors more dissatisfied with curtailed educational opportunities. That’s one conclusion of a new study published online March 20 in the New England Journal of Medicine.
Released: March 17, 2018

A standard swallow screening administered by a trained nurse may in some cases help clinicians more simply and quickly identify stroke patients at risk for dysphagia, a swallowing disorder that can lead to aspiration pneumonia.
Released: March 15, 2018

Surgical site infections are the most frequent health care-associated infections in developing countries. According to the World Health Organization (WHO), this type of infection can affect up to one-third of surgical patients in those nations.

Released: March 15, 2018

Using human brain cells, researchers piece together the cellular mechanisms that cause plaques to form in the brain

Working with lab-grown human brain cells, Johns Hopkins researchers report they have uncovered a much sought-after connection between one of the most common genetic mutations in Parkinson’s disease and the formation of fatty plaques in the brain thought to contribute to the destruction of motor neurons that characterize the disease.

Released: March 15, 2018

In a new Johns Hopkins study, researchers have added to evidence that Trichomonas vaginalis (TV), the world’s most common curable sexually transmitted infection (STI), disproportionately affects the black community.

Released: March 14, 2018

The wait is almost over for students who will soon graduate from the Johns Hopkins University School of Medicine: At noon on Friday, March 16, they will come together and open the envelopes that let them know where they will spend the next chapter of their lives training for careers in the medical field of their choosing.
Released: March 14, 2018

In a study conducted in rural India, Johns Hopkins Medicine researchers working in collaboration with Bal Umang Drishya Sanstha (BUDS), a nonprofit Indian organization focused on child health, have found that mobile phone reminders linked with incentives such as free talk time minutes work better than phone alerts alone to improve childhood immunization rates in poor communities.

Released: March 14, 2018

Gold standard method to preserve tissue for research or clinical use called into question

A method currently used by thousands of laboratories across the country to preserve tissue could render samples useless over time for a common test to assess gene activity, a study led by Johns Hopkins researchers suggests. The findings, published in the November 2, 2017 American Journal of Clinical Pathology, could eventually lead to significant changes in how tissues are stored for clinical and research purposes.

Released: March 9, 2018

Animal study reveals a skin itch receptor contributes to airway constriction

Working with mice, Johns Hopkins researchers report they have found previously known skin itch receptors in the airways that appear to contribute to bronchoconstriction and airway hypersensitivity, hallmarks of asthma and other respiratory disorders. The investigators’ experiments in mice suggest that the receptors’ activation directly aggravates airway constriction and—if the same process is active in people—may be a promising new target for the development of drug therapies.
Released: March 7, 2018

Working with cells grown in the lab, Johns Hopkins researchers have identified a biochemical pathway that allows a structure within cells, called the Golgi apparatus, to combat stress caused by free radicals and oxidants. The research team showed that this pathway can be activated by a drug called monensin, which is commonly used as an antibiotic in animal feed.

Released: March 7, 2018

Johns Hopkins experts present at CROI 2018.
Released: March 6, 2018

Claude Migeon, M.D., the director of pediatric endocrinology at the Johns Hopkins University School of Medicine from 1961 to 1994 and the scientist whose early focus on steroid metabolism established the norms of adrenal function in infancy and childhood, died on March 4. He was 94.

Released: March 6, 2018

“Understudied” condition found to progress slowly

By measuring the sagging of the vaginal walls in more than a thousand volunteers for up to nine years annually, a team of Baltimore physicians reports the creation of a long-awaited baseline measure of the rate of progression of so-called pelvic organ prolapse. The baseline, they say, should provide a foundation for reliable studies and a more rational search for factors that prevent or ease the condition.

Released: March 6, 2018

Mouse study suggests poor childhood bone mass may result from early “retirement” of bone cell precursors

By studying mice in late adolescence, Johns Hopkins University researchers have discovered that the rapid bone growth associated with puberty is slowed not only by fewer cartilage cell divisions but also by the “aging” of bone cell precursor cells. After investigating the signaling molecules that promote this transition, the scientists conclude that some weak and brittle bone conditions in both children and adults may be due to the cells’ premature “retirement” caused by glucocorticoid treatments given during puberty to treat chronic inflammation resulting from rheumatoid disorders and other diseases.

Released: March 5, 2018

In a small study, doctors at Johns Hopkins have successfully transplanted 10 hepatitis C-infected kidneys into patients without hepatitis C and prevented the patients from becoming infected by hepatitis C. The success of these transplants could mean more organs being available for the nearly 100,000 people in the U.S. currently waiting for a kidney transplant.

Released: March 5, 2018

Pioneering scientist Murray B. Sachs, Ph.D., who led the biomedical engineering department at Johns Hopkins for 16 years, died March 3 after a long illness. He was 77.

Released: March 5, 2018

A new strategy by Johns Hopkins researchers gives scientists a biologically informed way to select genes to study

A genetics research team at Johns Hopkins Medicine has solved a dilemma facing researchers who use genomewide association studies (GWAS) by developing a new approach that strategically “filters” which genes are worth further study. The researchers hope this strategy will accelerate the study of diseases such as Parkinson’s, Alzheimer’s, schizophrenia and even addiction by helping researchers avoid “dead-end paths.” They are optimistic that this strategy will gain widespread use and will save researchers time and money.

Released: March 5, 2018

Underutilization a “Missed Opportunity” to Lower Costs and Improve Outcomes for Those on Medicare

A study of more than 200,000 Medicare patients who had common surgical procedures shows that, compared to the general population, they underwent far fewer minimally invasive operations, whose benefits include lower rates of complications and readmissions, along with shorter hospital stays.

Released: March 1, 2018

Johns Hopkins researchers have invented a new class of cancer immunotherapy drugs that are more effective at harnessing the power of the immune system to fight cancer. This new approach, which was reported in Nature Communications, results in a significant decrease of tumor growth, even against cancers that do not respond to existing immunotherapy.

Released: February 28, 2018

A new Medicare records study by Johns Hopkins researchers has added to mounting evidence that a common surgery designed to remove damaged, worn ends of the thin rubbery cartilage in the knee joint brings little or no benefit to people over the age of 65.

Released: February 28, 2018

New study represents a key step toward improving the quality of care for transgender patients, authors say

In a national medical records analysis, researchers at Johns Hopkins Medicine say there is evidence that the number of gender affirming surgeries performed in hospitals for transgender individuals is on the rise, along with increased access made possible by Medicare, Medicaid or private insurance coverage for the procedures.

Released: February 26, 2018

Research led by Johns Hopkins physicians and scientists shows that a test for measuring the length of DNA endcaps, called telomeres, which has a variability rate of 5 percent, can alter treatment decisions for patients with certain types of bone marrow failure.
Released: February 23, 2018

Johns Hopkins has a range of experts available for interviews and comments about seasonal flu, infection control, flu transmission in children and flu treatment.

Released: February 22, 2018

Could help refine biomarkers of cancer risk

Some scientists have hypothesized that tumor-promoting changes in cells during cancer development—particularly an epigenetic change involving DNA methylation—arise from rogue cells escaping a natural cell deterioration process called senescence. Now, researchers at the Johns Hopkins Kimmel Cancer Center demonstrated that instead, tumor-associated epigenetic states evolve erratically during early stages of tumor development, eventually selecting for a subset of genes that undergo the most changes during normal aging and in early tumor development.

Released: February 21, 2018

In what is believed to be the largest pancreatic cancer genome-wide association study to date, researchers at the Johns Hopkins Kimmel Cancer Center and the National Cancer Institute, and collaborators from over 80 other institutions worldwide discovered changes to five new regions in the human genome that may increase the risk of pancreatic cancer.

Released: February 20, 2018

In an analysis of clinical data collected on more than 9,000 people, Johns Hopkins researchers have shown that the number of years spent overweight or obese appear to “add up” to a distinct risk factor that makes those with a longer history of heaviness more likely to test positive for a chemical marker of so-called “silent” heart damage than those with a shorter history
Released: February 20, 2018

Researchers call for “standard pricing” legislation to reduce financial burdens of vulnerable patients

An analysis of recent Medicare billing records for more than 3,000 hospitals across the United States shows that charges for outpatient oncology services such as chemo infusion or radiation treatment vary widely and exceed what Medicare will pay by twofold to sixfold.

Released: February 13, 2018

As the Winter Olympics begin, the world will be marveling at feats performed by athletes at the top of their game. But how do judges distinguish, in just a split second, a gold medal-winning performance from a silver?
Released: February 12, 2018

In an editorial that draws on results of previously published studies and experiences in their medical intensive care unit (ICU), a team of Johns Hopkins Medicine professionals say that bringing specially trained dogs into ICUs can safely and substantially ease patients’ physical and emotional suffering.

Released: February 12, 2018

Below are brief summaries of story ideas for February’s Valentine’s Day and American Heart Month
Released: February 12, 2018

Johns Hopkins researchers report successful use of heart imaging to predict the benefit or futility of catheter ablation, an increasingly popular way to treat atrial fibrillation, a common heart rhythm disorder.

Released: February 9, 2018

The Johns Hopkins University School of Medicine’s Brancati Center will provide free community health screenings this Saturday, Feb. 10, at A Family Affair, an event hosted by Living Classrooms. RSVP encouraged: email or call (443) 835-1463 x667 to register.

Released: February 8, 2018

Johns Hopkins researchers report they have developed two new endoscopic probes that significantly sharpen the technology’s imaging resolution and permit direct observation of fine tissue structures and cell activity in small organs in sheep, rats and mice
Released: February 7, 2018

Findings suggest opportunity to increase organ supply, save lives

In a new Johns Hopkins study of patient and graft survival trends for pediatric liver transplant recipients between 2002 and 2015, researchers found that outcomes for alternatives to whole liver transplantation (WLT), such as splitting a liver for two recipients or using a part of a liver from a living donor, have improved significantly.
Released: February 6, 2018

A new Johns Hopkins study of mice with the rodent equivalent of metabolic syndrome has added to evidence that the intestinal microbiome — a “garden” of bacterial, viral and fungal genes — plays a substantial role in the development of obesity and insulin resistance in mammals, including humans.
Released: February 5, 2018

After years of investigation, researchers at Johns Hopkins, the University of California, Davis, and the National Institute of Allergy and Infectious Diseases have discovered how the immune system might protect a person from recurrent bacterial skin infections caused by Staphylococcus aureus (staph).
Released: February 5, 2018

Enrolling in Medicaid may have health benefits not only for low-income parents but also for their children, according to a Johns Hopkins analysis of over 50,000 parent-child pairs.

Released: February 1, 2018

$50 million gift to transform research and care of stroke globally

A new institute for stroke research and clinical care was announced today by the United Arab Emirates (UAE) Embassy in Washington, D.C., and Johns Hopkins. The Sheikh Khalifa Stroke Institute, funded by a $50 million gift from the United Arab Emirates, will focus Johns Hopkins’ efforts to leverage advances in engineering, artificial intelligence and precision medicine to better diagnose, treat and restore function to stroke patients. The gift is believed to be the largest ever for a stroke-specific initiative.  
Released: February 1, 2018

Two species may work together to drive tumor formation in hereditary colon cancer syndrome and sporadic colon cancer

Patients with an inherited form of colon cancer harbor two bacterial species that collaborate to encourage development of the disease, and the same species have been found in people who develop a sporadic form of colon cancer, a study led by a Johns Hopkins Bloomberg~Kimmel Institute for Cancer Immunotherapy research team finds.
Released: February 1, 2018

In a study of 61 people treated for the bacteria that causes Lyme disease, Johns Hopkins researchers conclude that fatigue, pain, insomnia and depression do indeed persist over long periods of time for some people, despite largely normal physical exams and clinical laboratory testing.
Released: January 30, 2018

Today, the Global Council on Brain Health (GCBH), an independent collaborative of international scientists, health professionals, scholars and policy experts convened by AARP, published Brain Food
Released: January 24, 2018

New research discovers two proteins pivotal to maintaining cancer stem cells, which cause chemotherapy resistance

Two different proteins work separately as well as synergistically to feed a small pool of stem cells that help bladder cancer resist chemotherapy, research led by a Johns Hopkins Kimmel Cancer Center scientist suggests. The finding, published online in Cancer Research, could lead to new targets to fight this deadly disease and potentially other cancers as well.

Released: January 24, 2018

Through the haze of a sonogram screen, an expectant mother catches a glimpse of the growing baby within her. The outline of a nose, chin and head, instantly recognizable as a tiny human, brings to life what parents, until then, could only imagine. Biologists, too, aim to bring their scientific discoveries to life by creating three-dimensional models—at the atomic level—of the inner workings of cells.
Released: January 23, 2018

Despite efforts over the past two decades to increase the number of black and Hispanic patients receiving kidney transplants from related or unrelated living donors, these racial/ethnic minority patients are still much less likely to undergo such transplants than white patients, Johns Hopkins researchers report. In fact, the investigators say, the disparities have worsened in the last 20 years.

Released: January 22, 2018

Johns Hopkins researcher and his team describe an approach they say could transform the field of diagnostic quality and safety

In an effort to reduce patient misdiagnoses and associated poor patient outcomes from lack of prompt treatment, a Johns Hopkins Armstrong Institute for Patient Safety and Quality researcher is helping to lead the way in providing hospitals a new approach to quantify and monitor diagnostic errors in their quality improvement efforts. The approach, called Symptom-Disease Pair Analysis of Diagnostic Error, or SPADE, is featured in a paper published today in BMJ Quality & Safety.

Released: January 22, 2018

In an assessment of their “depression literacy” program, which has already been taught to tens of thousands, Johns Hopkins researchers say the Adolescent Depression Awareness Program (ADAP) achieved its intended effect of encouraging many teenagers to speak up and seek adult help for themselves or a peer. 

Released: January 18, 2018

Provides unique new framework for early detection of the most common cancers

Johns Hopkins Kimmel Cancer Center researchers developed a single blood test that screens for eight common cancer types and helps identify the location of the cancer.

Released: January 18, 2018

Data collected during a long-term health study provides additional evidence for a link between increased risk of cancer in individuals with advanced gum disease, according to a new collaborative study led by researchers at the Johns Hopkins Bloomberg School of Public Health, Johns Hopkins Kimmel Cancer Center and Tufts University School of Medicine and Cancer Center.
Released: January 16, 2018

Experiments with a small group of overweight men and women have added to evidence that “hunger hormone” levels rise and “satiety (or fullness) hormone” levels decrease in the evening. The findings also suggest that stress may increase hunger hormone levels more in the evening, and the impact of hormones on appetite may be greater for people prone to binge eating.

Released: January 16, 2018

A new study that seeks to ascertain HIV mortality rates in Zambia could provide a model for improved national and regional surveillance approaches and, ultimately, more effective HIV treatment strategies.

Released: January 11, 2018

Johns Hopkins hopes to become the first hospital in the U.S. to perform HIV-positive to HIV-positive organ transplants from living donors.

Released: January 10, 2018

What is precision medicine? It’s the practice of tailoring specific treatments to individual patients. Sometimes this involves making connections between a patient’s distinct genetic code and treatments that target that code, but it also takes into account a patient’s environment and lifestyle. Rather than the typical approach of prescribing treatments based on averages among patient populations, precision medicine has been the rallying cry of health care experts longing for better ways to match patients with customized care.
Released: January 8, 2018

Leading Causes of Death Are Prematurity and Injuries

In a new study of childhood mortality rates between 1961 and 2010 in the United States and 19 economically similar countries, researchers report that while there’s been overall improvement among all the countries, the U.S. has been slowest to improve.

Released: January 8, 2018

Johns Hopkins scientists have used a form of artificial intelligence to create a map that compares types of cellular receptors, the chemical “antennas” on the surface of immune system T-cells. Their experiments with lab-grown mouse and human T-cells suggest that people with cancer who have a greater variety of such receptors may respond better to immunotherapy drugs and vaccines.

Released: January 4, 2018

Project funded by collaboration between The Johns Hopkins University and Deerfield Management aims to develop first-in-class small molecule drug

Bluefield Innovations, a collaboration between The Johns Hopkins University and Deerfield Management to catalyze early stage therapeutic development, announced today the acceptance and funding of its first project. The target, the enzyme RNA polymerase I (Pol I), is implicated in many forms of cancer.
Released: January 3, 2018

Epilepsy drug reverses anti-social behaviors in mice with genes that produce variant proteins

Researchers at Johns Hopkins Medicine report they have identified rare genetic variations in a protein called Thorase, which is responsible for breaking down receptors at the connections between neurons in the brain.
Released: January 3, 2018

Johns Hopkins Medicine International (JHI) and the National Healthcare Group (NHG) today announced that their 20-year partnership has progressed to a new phase, with their Johns Hopkins Singapore International Medical Centre (JHSIMC) joint venture evolving into the new NHG-Johns Hopkins Singapore Institute.
Released: January 2, 2018

Studies suggest potential for reversing progressive vision loss

Johns Hopkins researchers have discovered a cell signaling pathway in mice that triggers vision loss in patients with diabetic retinopathy and retinal vein occlusion – diseases characterized by the closure of blood vessels in the retina, leading to blindness. In experiments that suppressed vascular endothelial growth factor (VEGF) in the eye, researchers were able to re-establish normal blood flow in the retina, offering a potential means of stalling or even reversing diabetes-related blindness.

Released: January 2, 2018

Assessment shown to be more accurate than a standard test for nonfasters

In a direct comparison study, Johns Hopkins researchers have added to evidence that a newer method of calculating so-called “bad cholesterol” levels in the blood is more accurate than the older method in people who did not fast before blood was drawn.