The Research

Interests and Goals:

• Dissecting the subcellular molecular changes that turn a normal thyroid cell into a cancer cell and identifying new therapeutics targeting these changes.
• Using transgenic zebrafish and human cell lines, Prescott and his lab team are developing high-throughput screening systems for identification of new anti-thyroid cancer drugs. 

Main Grants: 

• The Johns Hopkins Ross Physician Scientist Endowment
• The American Thyroid Association
• The American Association of Endocrine Surgeons

Highlights of Zebrafish Research:

Developed a number of live transgenic fish with fluorescent thyroids for use in studies of both normal thyroid development and of thyroid cancer development.  

Recent Advancements:

Developing transgenic zebrafish needed to perform high-throughput screening for new anti-thyroid cancer drugs.