When word started spreading on social media last year that Johns Hopkins laryngologist Lee Akst treats “no burp” syndrome, he soon began to receive a steady stream of calls.

Many of the patients who found Akst were just learning about this condition, medically referred to as retrograde cricopharyngeal dysfunction, or RCPD. Although the details from each caller varied, the gist of their stories was the same: None of them could burp.

In characterizing the experience of his patients, Akst explains that RCPD is more of a discomfort than a disability, but those with this condition can suffer significantly from its effects.

Patients with RCPD cannot orally expel gas, and this can cause them substantial pain, Akst says. The audible gurgling from trapped gas can also lead to social anxiety. His patients have shared numerous anecdotes about having to leave events early because of their discomfort, or being embarrassed because other people could hear their digestive noises. With no other options, patients often administer their own self-treatment called “air vomiting,” in which they induce vomiting simply to expel excess air.

Initial attempts at diagnosis of patients may include esophagoscopy, videofluoroscopic swallow evaluation, and manometry. Results typically aren’t remarkable, Akst says, and some clinicians may tell them there’s nothing wrong. But those with RCPD don’t always need to suffer, he says.

As one of the relatively few otolaryngologist–head and neck surgeons treating the condition, he offers a therapy that can sometimes solve this problem permanently. When patients who suspect they have RCPD book an appointment with Akst, he listens to their medical history to confirm that their symptoms match the disorder’s profile. After making sure that they have no swallowing problems or reflux — both of which can worsen with RCPD treatment — they book an appointment for an outpatient procedure.

Akst prefers to perform the procedure in an operating room and to place patients under general anesthesia to ensure precise treatment. He injects the cricopharyngeal sphincter with botulinum toxin and dilates it with a balloon. These steps relax the sphincter, allowing gas from the esophagus to escape through the mouth as a burp.

For the first few weeks after treatment, Akst says, burping can be “exuberant,” with patients having little control over escaping gas. Passing food through the sphincter while swallowing might also feel slower, and patients might experience increased acid reflux. But over time, these side effects tend to decrease. Although the effects of the botulinum toxin injection wear off after several months, about 90% of RCPD patients continue to burp normally, potentially because they have relearned how to control the cricopharyngeal sphincter, Akst explains.