In This Section      
 

Sherita Golden, MD, MHS

Ciccarone Center Research

Published By

Sherita Golden, MD, MHS

Sherita Golden, MD, MHS
Golden, Sherita, MD, MHS

Sherita Golden, MD, MHS, is the Director of Inpatient Diabetes Management Service and a Professor of Medicine.

View my Johns Hopkins Medicine profile for more information and to request an appointment.

 

Landmark Article

High-priority research needs for insulin delivery and glucose monitoring methods.

By: Yeh HC, Lau BD, Golden SH, Donner T, Brown TT, Bass EB.
This article summarizes future research needs in the area of technologies for insulin delivery and glucose monitoring methods.

Validity of meta-analysis in diabetes: meta-analysis is an indispensable tool in evidence synthesis.

By: Golden SH, Bass EB.
This article presents supporting arguments to support the use for meta-analysis in diabetes clinical research in a pro-con debate.

Pathways to quality inpatient management of hyperglycemia and diabetes: A call to action.

By: Draznin B, Gilden J, Golden SH, Inzucchi SE; PRIDE investigators.
This paper outlines eight aspects of inpatient glucose management (four as system-based issues and four as patient-based issues) in which randomized clinical trials are needed, and urges further progress in the science of inpatient diabetes management.

Relationship between the cortisol awakening response and other features of the diurnal cortisol rhythm: The Multi-Ethnic Study of Atherosclerosis.

By: Golden SH, Sanchez BN, Wu M, Champaneri S, Diez Roux AV, Seeman T, Wand GS.
Researchers for this study conclude that bedtime cortisol showed the strongest correlation with total cortisol area under the curve, suggesting it may be a marker of daily cortisol exposure.

Sex steroid levels and response to weight loss interventions among postmenopausal women in the Diabetes Prevention Program.

By: Kim C, Barrett-Connor E, Randolph JF, Kong S, Nan B, Mather K, Golden SH and the Diabetes Prevention Program Research Group.

This study found that, among nonestrogen users, baseline sex steroids were not associated with reductions in weight or waistline circumference.

The association of elective hormone therapy with changes in lipids among glucose intolerant postmenopausal women in the diabetes prevention program.

By: Golden SH, Kim C, Barrett-Connor E, Nan B, Kong S, Goldberg R; the Diabetes Prevention Program Research Group.

It is unclear how lipids change in response to lifestyle modification or metformin among postmenopausal glucose intolerant women using and not using hormone therapy (HT). We examined the one-year changes in lipids among postmenopausal, prediabetic women in the Diabetes Prevention Program (DPP), and whether changes were mediated by sex hormones. The beneficial effects of ILS and metformin on lowering LDL-C and raising HDL-C differ depending upon concurrent HT use.

Christopher Dyer Saudek, MD: diabetes expert and implantable insulin pump pioneer.

By: Golden SH, Kalyani RR, Donner T.

Endocrine and inflammatory profiles in type 2 diabetic patients with and without major depressive disorder.

By: Alvarez A, Faccioli J, Guinzbourg M, Castex MM, Bayón C, Masson W, Bluro I, Kozak A, Sorroche P, Capurro L, Grosembacher L, Proietti A, Finkelsztein C, Costa L, Day PF, Cagide A, Litwak LE, Golden SH.
This study found that diabetic patients with depression are more likely to have cardiovascular events, and different factors can determine this high association.

Metabolic syndrome risk profiles among African American adolescents: national health and nutrition examination survey, 2003-2010.

By: Fitzpatrick SL, Lai BS, Brancati FL, Golden SH, Hill-Briggs F.

Although African-American adolescents have the highest prevalence of obesity, they have the lowest prevalence of metabolic syndrome across all definitions used in previous research. To address this paradox, we sought to develop a model of the metabolic syndrome specific to African-American adolescents. Our findings provide a plausible model of the metabolic syndrome specific to African-American adolescents. Based on this model, approximately 19% and 16% of African-American boys and girls, respectively, are at high risk for having the metabolic syndrome.

Hypoglycemia in non-critically ill, hospitalized patients with diabetes: evaluation, prevention, and management.

By: Rubin J, Golden SH.

Hypoglycemia among hospitalized patients with diabetes is a common problem. Of the > 8 million patients admitted to US hospitals annually with a diagnosis of diabetes, up to 25% may have a low blood glucose level during hospitalization. As a widely recognized cause of acute, potentially fatal events, hypoglycemia remains a significant barrier to optimal inpatient glycemic control. Although iatrogenic hypoglycemia is associated with adverse outcomes, it may be a marker for illness rather than causal in itself. Several factors, such as administration of exogenous insulin, mismatch of insulin administration with nutrition, and the loss of normal counterregulatory responses, place patients with diabetes at higher risk for hypoglycemia than patients without diabetes. Causes and predictors of hypoglycemia in hospitalized patients with diabetes are discussed. Careful attention to contributing factors, responsiveness to changes in clinical status, and specific institutional protocols and policies can reduce the risk of hypoglycemia. Use of subcutaneous basal-bolus insulin dosing consistent with national guidelines and correction rather than sliding-scale insulin may minimize both hyper- and hypoglycemia. A majority of the literature on inpatient hypoglycemia has been limited to the critical-care setting. This review therefore focuses on hypoglycemia among non-critically ill inpatients with diabetes.