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School of Medicine
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Sherita Golden, MD, MHS
Ciccarone Center Research
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- Meet the Authors
Health disparities in endocrine disorders: Biological, clinical, and nonclinical factors — an Endocrine Society Scientific Statement.There is little evidence that genetic differences contribute significantly to race/ethnic disparities in the endocrine disorders examined. Multilevel interventions have reduced disparities in diabetes care, and these successes can be modeled to design similar interventions for other endocrine diseases.Read on Pubmed
High-priority research needs for insulin delivery and glucose monitoring methods.
Validity of meta-analysis in diabetes: meta-analysis is an indispensable tool in evidence synthesis.
Pathways to quality inpatient management of hyperglycemia and diabetes: A call to action.
This paper outlines eight aspects of inpatient glucose management (four as system-based issues and four as patient-based issues) in which randomized clinical trials are needed, and urges further progress in the science of inpatient diabetes management.
Relationship between the cortisol awakening response and other features of the diurnal cortisol rhythm: The Multi-Ethnic Study of Atherosclerosis.
Sex steroid levels and response to weight loss interventions among postmenopausal women in the Diabetes Prevention Program.
The association of elective hormone therapy with changes in lipids among glucose intolerant postmenopausal women in the diabetes prevention program.
It is unclear how lipids change in response to lifestyle modification or metformin among postmenopausal glucose intolerant women using and not using hormone therapy (HT). We examined the one-year changes in lipids among postmenopausal, prediabetic women in the Diabetes Prevention Program (DPP), and whether changes were mediated by sex hormones. The beneficial effects of ILS and metformin on lowering LDL-C and raising HDL-C differ depending upon concurrent HT use.
Christopher Dyer Saudek, MD: diabetes expert and implantable insulin pump pioneer.
Endocrine and inflammatory profiles in type 2 diabetic patients with and without major depressive disorder.
Metabolic syndrome risk profiles among African American adolescents: national health and nutrition examination survey, 2003-2010.
Although African-American adolescents have the highest prevalence of obesity, they have the lowest prevalence of metabolic syndrome across all definitions used in previous research. To address this paradox, we sought to develop a model of the metabolic syndrome specific to African-American adolescents. Our findings provide a plausible model of the metabolic syndrome specific to African-American adolescents. Based on this model, approximately 19% and 16% of African-American boys and girls, respectively, are at high risk for having the metabolic syndrome.
Hypoglycemia in non-critically ill, hospitalized patients with diabetes: evaluation, prevention, and management.
Hypoglycemia among hospitalized patients with diabetes is a common problem. Of the > 8 million patients admitted to US hospitals annually with a diagnosis of diabetes, up to 25% may have a low blood glucose level during hospitalization. As a widely recognized cause of acute, potentially fatal events, hypoglycemia remains a significant barrier to optimal inpatient glycemic control. Although iatrogenic hypoglycemia is associated with adverse outcomes, it may be a marker for illness rather than causal in itself. Several factors, such as administration of exogenous insulin, mismatch of insulin administration with nutrition, and the loss of normal counterregulatory responses, place patients with diabetes at higher risk for hypoglycemia than patients without diabetes. Causes and predictors of hypoglycemia in hospitalized patients with diabetes are discussed. Careful attention to contributing factors, responsiveness to changes in clinical status, and specific institutional protocols and policies can reduce the risk of hypoglycemia. Use of subcutaneous basal-bolus insulin dosing consistent with national guidelines and correction rather than sliding-scale insulin may minimize both hyper- and hypoglycemia. A majority of the literature on inpatient hypoglycemia has been limited to the critical-care setting. This review therefore focuses on hypoglycemia among non-critically ill inpatients with diabetes.