In This Section      
 

Roger S. Blumenthal, MD

Ciccarone Center Research

Published By

Roger S. Blumenthal, MD

Roger S. Blumenthal, MD
Blumenthal, Roger S., MD

Roger S. Blumenthal, MD is Director of the Johns Hopkins Ciccarone Center for the Prevention of Heart Disease and a Professor of Medicine.

View my Johns Hopkins Medicine profile for more information and to request an appointment.
 
 

Landmark Articles

Nonfatal outcomes in the primary prevention of atherosclerotic cardiovascular disease: is all-cause mortality really all that matters?

By: Czarny MJ, Martin SS, Kohli P, Metkus T, Blumenthal RS.
This article clearly shows that major nonfatal cardiovascular outcomes are very important to take into account when designing primary prevention guidelines.

Baseline subclinical atherosclerosis burden and distribution are associated with frequency and mode of future coronary revascularization: multi-ethnic study of atherosclerosis.

By: Silverman MG, Harkness JR, Blankstein R, Budoff MJ, Agatston AS, Carr JJ, Lima JA, Blumenthal RS, Nasir K, Blaha MJ.
There was a strong association between the baseline burden and regional distribution of CAC and the risk and type of future coronary revascularization among asymptomatic subjects.

Delayed heart rate recovery is strongly associated with early and late stage prehypertension during exercise stress testing.

By: Aneni E, Roberson LL, Shaharyar S, Blaha MJ, Agatston A, Blumenthal RS, Meneghelo RS, Conceiçao RD, Nasir K, Santos RD.
Among asymptomatic patients undergoing stress testing delayed HRR was independently associated with early and late stages of prehypertension. Further studies are needed to determine the usefulness of HRR measure in the prevention and management of hypertension.

2013 ACC/AHA Guideline on the treatment of blood cholesterol to reduce atherosclerotic cardiovascular risk in adults.

By: Abd TT, Misra S, Ojeifo O, Martin SS, Blumenthal RS, Foody J, Wong ND.

Narrowing sex differences in lipoprotein cholesterol subclasses following mid-life: the very large database of lipids (VLDL-10B).

By: Swiger KJ, Martin SS, Blaha MJ, Toth PP, Nasir K, Michos ED, Gerstenblith G, Blumenthal RS, Jones SR.
The narrowing sex differential in CVD risk after midlife is mirrored by a higher total atherogenic lipoprotein cholesterol burden in women and a closer approximation of the less favorable density phenotype characteristic of men.

2013 AHA/ACC/TOS guideline for the management of overweight and obesity in adults.

By: Abd TT, Misra S, Ojeifo O, Martin SS, Blumenthal RS, Foody J, Wong ND.
The authors sought to answer five critical questions, addressing 1) expected health benefits of weight loss; 2) cut points for body mass index (BMI) and waist circumference; 3) dietary interventions most effective for weight loss; 4) the efficacy of a comprehensive lifestyle intervention programs; and 5) bariatric surgery.

Screening low-risk individuals for coronary artery disease.

By: Desai CS, Blumenthal RS, Greenland P.
Data regarding the role of additional testing in low-risk populations to improve early detection or to enhance risk assessment indicate that CAC and the ankle-brachial index (ABI) may be helpful for improving risk classification and detecting the higher-risk people from among those at lower risk.

Fatty acids and TxA2 generation, in the absence of platelet-COX-1 activity.

By: DeFilippis AP, Rai SN, Cambon A, Miles R, Saenger AK, Blumenthal RS, Jaffe AS, Moser AB, Jones RO, Bolli R, Schulman SP.
This study shows that baseline omega-3 fatty acid levels do not influence TxA(2) generation in patients with or at high risk for CVD receiving adequate aspirin therapy.

Ethnic and sex differences in fatty liver on cardiac computed tomography: the multi-ethnic study of atherosclerosis.

By: Tota-Maharaj R, Blaha MJ, Zeb I, Katz R, Blankstein R, Blumenthal RS, Budoff MJ, Nasir K.
African-Americans have a lower prevalence, and Hispanics have a higher prevalence, of fatty liver than do other ethnicities. There are distinct ethnic variations in the prevalence of fatty liver even in patients with the metabolic syndrome or obesity, suggesting that genetic factors may play a substantial role in the phenotypic expression of fatty liver.

Ten-year trends in coronary calcification in individuals without clinical cardiovascular disease in the multi-ethnic study of atherosclerosis.

By: Bild DE, McClelland R, Kaufman JD, Blumenthal R, Burke GL, Carr JJ, Post WS, Register TC, Shea S, Szklo M.

Researchers reported a significant secular trend toward increased prevalence of CAC over 10 years among African-Americans and no change in three other ethnic groups..