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Niacin — a case study for the role of event-driven versus surrogate endpoint trials.
By: Blaha MJ, Michos ED.
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Electrocardiographic and clinical predictors separating atherosclerotic sudden cardiac death from incident coronary heart disease.
By: Soliman EZ, Prineas RJ, Case LD, Russell G, Rosamond W, Rea T, Sotoodehnia N, Post WS, Siscovick D, Psaty BM, Burke GL.
Sudden cardiac death and coronary heart disease have many risk factors in common, including hypertension, race/ethnicity, BMI, and heart rate, that have the potential to separate between the risks of both diseases. These results need to be validated in another cohort.
Read on Pubmed
Electrocardiographic and clinical predictors separating atherosclerotic sudden cardiac death from incident coronary heart disease.
By: Soliman EZ, Prineas RJ, Case LD, Russell G, Rosamond W, Rea T, Sotoodehnia N, Post WS, Siscovick D, Psaty BM, Burke GL.
To identify specific ECG and clinical predictors that separate atherosclerotic SCD from incident CHD (non-fatal events and non-sudden death) in the combined cohorts of the Atherosclerosis Risk in Communities study and the Cardiovascular Health Study. This analysis included 18,497 participants (58% females, 24% black individuals, mean age 58 years) who were initially free of clinical CHD. SCD and CHD have many risk factors in common. Hypertension, race/ethnicity, BMI, heart rate, QTc, abnormally inverted T wave in any ECG lead group and level of ST elevation in V2 have the potential to separate between the risks of SCD and CHD. These results need to be validated in another cohort.
Read on Pubmed