Effects of physical activity on cardiovascular disease.
Much attention has been directed toward lifestyle modifications as effective means of reducing cardiovascular disease risk. We review recent observational and interventional trials investigating the effects of physical activity on markers of (or causal factors for) atherosclerotic burden and vascular disease. There is a strong correlation between physical activity and triglyceride reduction, apolipoprotein B reduction, HDL increase, change in LDL particle size, increase in tissue plasminogen activator activity, and decrease in CAC. Further research is needed to elucidate the effect on inflammatory markers and intima-media thickness.
- Journal: American Journal of Cardiology
- Year: 2012
- Topic: ASCVD (Atherosclerotic Cardiovascular Disease), Cholesterol / Lipids / Statins, Exercise and Physical Fitness, Markers of Thrombosis, Myocardial Injury, Wall Stress
- Read more articles by: Roger S. Blumenthal, MD, Michael Blaha, MD, MPH, Khurram Nasir, MD, MPH