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Chiadi Ndumele, MD, MHS

Ciccarone Center Research

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Chiadi Ndumele, MD, MHS

Chiadi Ndumele, MD, MHS
Ndumele, Chiadi, MD, MHS

Chiadi Ndumele, MD, MHS is an Assistant Professor of Medicine.

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Landmark Articles

Obesity, subclinical myocardial injury and incident heart failure.

By: Ndumele CE, Coresh J, Lazo ML, Hoogeveen RC, Blumenthal RS, Folsom AR, Selvin E, Ballantyne CM, Nambi V.

Two classic hemodynamic findings for hypertrophic cardiomyopathy.

By: Barth AS, Abraham T, Ndumele C, Zakaria S.

Exercise and physical activity for cardiovascular disease prevention.

APOE modulates the correlation between triglycerides, cholesterol, and CHD through pleiotropy, and gene-by-gene interactions.

By: Maxwell TJ, Ballantyne CM, Cheverud JM, Guild CS, Ndumele CE, Boerwinkle E.
The relationship between total cholesterol and triglycerides varies by apolipoprotein E isoform genotype in African-American and European-American populations.

Relation of hepatic steatosis to atherogenic dyslipidemia.

By: Makadia SS, Blaha M, Keenan T, Ndumele C, Jones S, DeFilippis A, Martin S, Kohli P, Conceicao R, Carvalho J, Nasir K, Blumenthal R, Santos RD.
Hepatic steatosis may play a direct metabolic role in conferring increased cardiovascular risk.

Relation of hepatic steatosis to atherogenic dyslipidemia.

By: Makadia S, Blaha MJ, Keenan T, Ndumele C, Jones S, DeFilippis A, Martin SS, Kohli P, Conceicao RD, Carvalho JA, Nasir K, Blumenthal RS, Santos R.
This article looks at the relationship between fatty liver and atherogenic lipid profiles.

ASK NOT what CRP can do for you.

By: Blumenthal RS, Ndumele CE, Martin SS.

This editorial examines the extent to which measurements of vascular inflammation can improve cardiovascular risk prediction.

Apolipoproteins do not add prognostic information beyond lipoprotein cholesterol measures among individuals with obesity and insulin resistance syndromes: The ARIC Study.

By: Ndumele CE, Matsushita K, Astor B, Virani SS, Mora S, Williams EK, Hoogeveen RC, Blumenthal RS, Sharrett AR, Ballantyne CM, Coresh J.
Among individuals with obesity and insulin resistance syndromes, apolipoproteins did not provide prognostic information regarding CHD risk beyond that provided by non-HDL-C and HDL-C.

The association of Framingham and Reynolds risk scores with incidence and progression of coronary artery calcification in MESA (Multi-Ethnic Study of Atherosclerosis).

By: DeFilippis AP, Blaha MJ, Ndumele CE, Budoff MJ, Lloyd-Jones DM, McClelland RL, Lakoski SG, Cushman M, Wong ND, Blumenthal RS, Lima J, Nasir K.
Both the Framingham and Reynolds risk scores predict onset and progression of subclinical atherosclerosis. However, the Reynolds risk score may provide additional predictive information when discordance between the scoring systems exists.

The association of the Framingham and Reynolds risk scores with incidence and progression of coronary artery calcium in MESA.

By: DeFilippis AP, Blaha MJ, Ndumele C, Budoff MJ, Lloyd-Jones D, McClelland RL, Lakoski SG, Cushman M, Wong ND, Blumenthal RS, Lima J, Nasir K.
This innovative study found that the Reynolds Risk Score was modestly better than the traditional Framingham risk score in predicting the incidence of new coronary calcification and the progression of existing calcification. This observation also applied to clinical events.