Transplant Research

Transplant Research
Outreach Newsletter 
Transplant Research Lecture Series    
Research Studies Index

Our physician newsletter, Outreach describes some of the latest transplant news and research advances at Hopkins.  Outreach is published two times a year by the Comprehensive Transplant Center. 

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For more information, please contact our Transplant Outreach Coordinator at telephone 443-287-2896.

Current Outreach Newsletter

Fivush, Barbara

• An Open-Label, Comparative Study of the Effect of Sirolimus Verus Standard Treatment on Clinical Outcomes and Histologic Progresssion of Allograft Nephropathy in High Risk Pediatric (Sponsor: New York Medical College)

Haas, Mark

• Cd3 Staining of Renal Transplant Biopsies (Sponsor: National Kidney Foundation of Maryland)

Montgomery, Robert

• Icam1 Gene Inactivation Protects Against Ischemic Injury (Sponsor: National Institutes of Health)
• Strategies for Silencing Gene That Potentiate Ischemic Reperfusion Injury (Sponsor: Advanced Cardiovascular Systems, Inc.)
• Abrogation of Humoral Immune Responses Utilizing Plasmapheresis/Cytogamin Positive Crossmatch & ABO Incompatible Donor/Recipient Pairs Undergoing Live Renal Transplantation (Sponsor: Imi International Medical Innovations Inc.)
• Enhanced Utilization of Extended Criteria and Non-Heart Beating Donor Kidneys (Sponsor: Health Resources and Services Administration)
• Gene Therapeutics for Marfan Disease (Sponsor: American College of Surgeons)
• Improved Utilzation of Cadaveric Kidneys (Sponsor: Health Resources and Services Administration)

Neu, Alicia

• Evaluation of Tacrolimus as Primary Immunosuppression in Pediatric Renal Transplant Patients (Sponsor: Fujisawa Healthcare, Inc.)

Rabb, Hamid

• T-Cells in Renal Ischemic Reperfusion Injury (Sponsor: National Institutes of Health/National Institute of Diabetes and Digestion and Kidney Disease)
• Randomized trial of high versus conventional dose dialysis for acute renal failure (Sponsor: National Institutes of Health/Veterans Administration Acute Renal Failure Dialysis)
• Acute Renal Failure and Ventilation Induced Lung Injury - T-Cells in Innate Inury (Sponsor: National Institutes of Health/National Heart, Lung, and Blood Institute)
• Sirolimus Effects Long Term After Ischemia Reperfusion (Sponsor: Wyeth Pharmaceuticals)
• Improved Utilization of Cadaveric Kidneys (Sponsor: Health Resources and Services Administration)
• Mechanisms of T-Cell Mediated Renal Ischemia Reperfusion (Sponsor: Roche Organ Transplantation Foundation)
  

Zachary, Andrea

• Mechanisms Mediating Donor-Specific Desensitization Induced by Plasmapheresis and Anti-Cmv Hyperimmune Immunoglobulin (Cytogam) in High Risk Renal Allograft Patients (Sponsor: MedImmune)
  

Rai, Rudra

• A Phase Iii Study of the Comparison of Entecavir Lamivudine in Chronic Hepatitis B Subjects with Incomplete Response to Current Lamivudine Therapy (Sponsor: Bristol Myers Squibb Company)
• A Phase Iii Study of the Safety and Antiviral Activity of Entecavir vs. Lammivudine in Adults with Chronic Hepatitis B Infection who are Negative for Hepatitis B E Antigen (Sponsor:Bristol Myers Squibb Company)
• A Phase Iii Study of the Safety and Antiviral Activity of Entecavir vs. Lammivudine in Adults with Chronic Hepatitis B Infection who are Positive for Hepatitis B E Antigen (Sponsor: Bristol Myers Squibb Company)
• Comparison of Peg Interferon Alfa-2b Plus Ribovirin Given as Fixed Dose or on Weight Optimized Basis for Treatment of Chronic Hepatitis C in Previously Untreated Adult Subjects (Sponsor: Schering Corporation)
• Dose Comparison Study of Peg-Interferon Alfa-2b+ Ribavirin for Patients with Chronic Hepatitis C Who Have Not Responded to Standard Interferon+Ribavirin (Sponsor: Schering Corporation)

Schwarz, Kathleen

• Novel Antigen an T&B Cell Responses in Biliary Atresia (Sponsor: National Institute of Diabetes and Digestive and Kidney Diseases)
• Viral Hepatitis in Children of Injection Drug Users (Sponsor: National Institute on Drug Abuse)

Thuluvath, Paul

• A Multicenter Double-Blinded Study in Patients with Compensated Cirrhosis Due to Chronic Hepatitis C Who Are Non-Responders to Prior Interferon Alfa or Interferon Alfa + Ribavirin Therapy, Comparing Treatment with Peginterferon Alfa-2a+Placebo Protocol Ta1-Chc-2k0804 (Sponsor: Sciclone Pharmaceuticals, Inc.)

Becker, Patrice

• Vascular Endothelial Growth Factor in Lung Ishchemia (Sponsor: National Heart, Lung, and Blood Institute)

Laube, Beth

• Optimizing the Intrapulmonary Delivery of Insulin Aerosol (Sponsor: INHALE)

Garcia, Joe

• Applied Genomics in Cardiopulmonary Medicine (Sponsor: National Heart, Lung, and Blood Institute)
• Cytoskeletal Regulation of Endothelial Cell Pathobiology (Sponsor: National Heart, Lung, and Blood Institute)
• Lung Vascular Barrier Perservation by Platelet Products (Sponsor: National Institutes of Health)

Mogayzel, Peter

• Regulation of Cftr Gene Expression (Sponsor: Cystic Fibrosis Foundation Therapeutics, Inc.)

Orens, Jonathan

• A Three Year Randomized, Multicenter, Double Blind, Parallel Group Study of the Efficacy and Safety of Sdz Rad Versus Azathioprine as Adjunctive Immunosuppressive Therapy to Inhibit the Decl... (Sponsor: Novartis)

Kasper, Edward

• Surgical Treatment for Ischemic Heart Failure (Sponsor: Duke Clinical Research Institute) 

Baldwin, William

• Complement Mediated Injury in Allograft Rejection (Sponsor: National Institute of Allergy and Infectious Diseases)

 Schneck, Jonathan

• Antigen-Specific Modulation of T Cell Responses (Sponsor: National Institute of Allergy and Infectious Diseases)
• Generation of Artificial Antigen Presenting Cells (Sponsor: National Heart, Lung, and Blood Institute)