Skip Navigation
Search Menu
Neurology and Neurosurgery

In This Section      
Print This Page

Myoclonic Astatic Epilepsy (Doose Syndrome)

What is myoclonic astatic epilepsy (Doose syndrome)? 

Myoclonic astatic epilepsy (MAE), also known as Doose syndrome, is an epilepsy syndrome of early childhood usually characterized by difficult to control generalized seizures. Children will experience drop and staring seizures, sometimes associated with falls.

Symptoms of myoclonic astatic epilepsy (Doose syndrome)

Generally resistant to medication, MAE is a difficult disorder to manage. Patients may experience several seizures daily, and MAE is idiopathic (has no known cause).

Most symptoms of myoclonic astatic epilepsy appear between ages one and five.

Treatment for myoclonic astatic epilepsy (Doose syndrome)

Anticonvulsant medications such as valproate and levetiracetam can be helpful for this condition. However, research in the past decade has shown that the ketogenic diet and modified Atkins diet can be the most effective treatment. 

Request an appointment

For more information about Doose syndrome or to meet with our doctors, request an appointment at the Epilepsy Center.

Request an Appointment

Maryland Patients

Thank you for considering the Epilepsy Center at Johns Hopkins.
Request an Appointment

Adult Neurology: 410-955-9441
Pediatric Neurology: 410-955-4259
Adult Neurosurgery: 410-955-6406
Pediatric Neurosurgery: 410-955-7337


Traveling for Care?

Whether you're crossing the country or the globe, we make it easy to access world-class care at Johns Hopkins.

Outside of Maryland (toll free)

Request an Appointment
Medical Concierge Services

International Patients

Request an Appointment
Medical Concierge Services

blue suitcase