For information on recent CRF news and events, visit the Cancer Prevention & Control website.
You can also download the CONQUEST, a publication of the Maryland Cigarette Restitution Fund and report on the CRF funds at Johns Hopkins.
The following is a sampling of CRF investigators whose research has made headlines.
CRF Scientist Seek ‘Swish and Spit’ Test for Cancer
CRF researcher Joseph Califano is working to develop a test that could detect the presence of certain cancers of the head and neck based on compounds found in saliva. A simple mouth rinse could be all it takes to capture genetic signatures common to head and neck cancers.
CRF Scientists Create 3-D image of Cancer Initiator
A growth-promoting gene called PIK3CA, linked to cancer by CRF investigator Victor Velculescu, is believed to be one of the most frequently mutated in cancer, and now we know what the enemy looks like. A research team from the Johns Hopkins University created a 3-D picture of the gene and, onto the model, mapped all cancer-associated mutations.
CRF Scientist Identifies Mutations Linked to Hereditary Lung Disease
Kimmel Cancer Center investigators, including CRF-funded Mary Armanios, have identified the genetic culprits that trigger a hereditary form of a fatal lung disease. The findings may provide new directions in diagnosis and treatment for families that inherit genes for the disease, as well as for those that develop noninherited forms of the illness.
HPV Causing More Oral Cancer in Men
According to a new study by CRF researcher Maura Gillison, the sexually transmitted virus that causes cervical cancer in women is poised to become one of the leading causes of oral cancer in men. Gillison’s findings have attracted the attention of cancer experts worldwide.
CRF Researcher Develops Vaccine to Protect Against Cervical Cancer
A 2001 CRF grant has allowed Dr. Connie Trimble to launch a clinical unit to screen women for early stages of cervical cancer; develop and test a vaccine to protect against cervical cancer in women infected with human papillomavirus (HPV); and study the reasons women are still developing cervical cancer in a time when screening is widely available.