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Gypsyamber D'Souza

Ph.D., M.P.H.
410-502-2583 (p)
Titles

Assistant Professor
Viral Oncology Program, Cancer Prevention & Control Program
Johns Hopkins Bloomberg School of Public Health

Research Summary

Dr D'Souza's primary research interest is in infectious causes of cancer. Current research explores the association between Human Papillomavirus (HPV) and oral, cervical and anal cancers, the natural history and concordance of oral and anogenital HPV infection, and HPV tropism.

Dr. D'Souza also has active research programs evaluating cancer screening methods and potential biomarkers. Additional interests include the role of behavioral factors on viral acquisition and persistence, epidemiology of sexually transmitted infections, the effect of viral load and drug use on disease progression, the epidemiology of HIV/AIDS, and infectious causes of AIDS malignancy.

 http://www.jhsph.edu/faculty/directory/profile/4577/D'Souza/Gypsyamber

Journal Citations

Fakhry, C.; D'Souza, G.; Sugar, E.; Weber, K.; Goshu, E.; Minkoff, H.; Wright, R.; Seaberg, E.; Gillison, M. The relationship between prevalent oral and cervical HPV infections in HIV-positive and negative women. J Clin Microbiol. 2006 Oct 4;44:4479-4485.
Fakhry, C.; D'Souza, G.; Sugar, E.; Weber, K.; Goshu, E.; Minkoff, H.; Wright, R.; Seaberg, E.; Gillison, M. Relationship between prevalent oral and cervical human papillomavirus infections in human immunodeficiency virus-positive and -negative women. J Clin Microbiol. 2006 Dec;44(12):4479-4485.
D'Souza, G.; Fakhry, C.; Sugar, E.A.; Seaberg, E.C.; Weber, K.; Minkoff, H.L.; Anastos, K.; Palefsky, J.M.; Gillison, M.L. Six-month natural history of oral versus cervical human papillomavirus infection. Int J Cancer. 2007 Jul 1;121(1):143-150.
D'Souza, G.; Kreimer, A.R.; Viscidi, R.; Pawlita, M.; Fakhry, C.; Koch, W.M.; Westra, W.H.; Gillison, M.L. Case-control study of human papillomavirus and oropharyngeal cancer. N Engl J Med. 2007 May 10;356(19):1944-1956.
Gillison, M.L.; D'Souza, G.; Westra, W.; Sugar, E.; Xiao, W.; Begum, S.; Viscidi, R. Distinct risk factor profiles for human papillomavirus type 16-positive and human papillomavirus type 16-negative head and neck cancers. J Natl Cancer Inst. 2008 Mar 19;100(6):407-420.
Adelstein, D.J.; Ridge, J.A.; Gillison, M.L.; Chaturvedi, A.K.; D'Souza, G.; Gravitt, P.E.; Westra, W.; Psyrri, A.; Kast, W.M.; Koutsky, L.A.; Giuliano, A.; Krosnick, S.; Trotti, A.; Schuller, D.E.; Forastiere, A.; Ullmann, C.D. Head and neck squamous cell cancer and the human papillomavirus: summary of a National Cancer Institute State of the Science Meeting, November 9-10, 2008, Washington, D.C. Head Neck. 2009 Nov;31(11):1393-1422.
Beachler, D.C.; D'Souza, G. Nuances in the changing epidemiology of head and neck cancer. Oncology (Williston Park). 2010 Sep;24(10):924, 926.
D'Souza, G.; Palefsky, J.M.; Zhong, Y.; Minkoff, H.; Massad, L.S.; Anastos, K.; Levine, A.M.; Moxley, M.; Xue, X.N.; Burk, R.D.; Strickler, H.D. Marijuana use is not associated with cervical human papillomavirus natural history or cervical neoplasia in HIV-seropositive or HIV-seronegative women. Cancer Epidemiol Biomarkers Prev. 2010 Mar;19(3):869-872.
D'Souza, G.; Zhang, H.H.; D'Souza, W.D.; Meyer, R.R.; Gillison, M.L. Moderate predictive value of demographic and behavioral characteristics for a diagnosis of HPV16-positive and HPV16-negative head and neck cancer. Oral Oncol. 2010 Feb;46(2):100-104.
Fakhry, C.; Sugar, E.; D'Souza, G.; Gillison, M. Two-week versus six-month sampling interval in a short-term natural history study of oral HPV infection in an HIV-positive cohort. PLoS One. 2010;5(7):e11918.
Marur, S.; D'Souza, G.; Westra, W.H.; Forastiere, A.A. HPV-associated head and neck cancer: a virus-related cancer epidemic. Lancet Oncol. 2010 Aug;11(8):781-789.
Minkoff, H.; Zhong, Y.; Burk, R.D.; Palefsky, J.M.; Xue, X.; Watts, D.H.; Levine, A.M.; Wright, R.L.; Colie, C.; D'Souza, G.; Massad, L.S.; Strickler, H.D. Influence of adherent and effective antiretroviral therapy use on human papillomavirus infection and squamous intraepithelial lesions in human immunodeficiency virus-positive women. J Infect Dis. 2010 Mar;201(5):681-690.
Xue, X.; Gange, S.J.; Zhong, Y.; Burk, R.D.; Minkoff, H.; Massad, L.S.; Watts, D.H.; Kuniholm, M.H.; Anastos, K.; Levine, A.M.; Fazzari, M.; D'Souza, G.; Plankey, M.; Palefsky, J.M.; Strickler, H.D. Marginal and mixed-effects models in the analysis of human papillomavirus natural history data. Cancer Epidemiol Biomarkers Prev. 2010 Jan;19(1):159-169.

 

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