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Stages of Alzheimer’s Disease

Alzheimer’s disease is a brain disorder that causes memory loss, confusion, and changes in personality. It is a type of dementia. At first, people with this disease have only a small amount of memory loss and confusion. This is called “cognitive decline.” Over time, however, these symptoms get more severe.

According to the Alzheimer's Association, the disease progresses through about seven stages of symptoms. In the final stage, people with Alzheimer’s disease may be unable to talk with family members or know what is going on around them.

This disease cannot be cured. Doctors and caregivers often focus treatment on slowing the process and ensuring a good quality of life for everyone involved.

More Information About Alzheimer's Disease from Johns Hopkins Medicine

Caretaker looks after a man with Alzheimer's disease

Beyond Memory Loss: How to Handle the Other Symptoms of Alzheimer's

There is a lot of talk about the emotional pain patients and caregivers suffer when a loved one loses memories to Alzheimer’s. But what about the other symptoms? Here are tips from a Johns Hopkins expert on what to watch for and how to manage.

Read more.

Facts about Alzheimer’s disease

Alzheimer’s disease is becoming more common as the general population gets older and lives longer. Alzheimer's disease usually affects people older than 65. A small number of people have “early-onset” Alzheimer’s disease, which starts when they are in their 30s or 40s.

People live for an average of eight years after their symptoms appear. But the disease can progress quickly in some people and slowly in others. Some people live as long as 20 years with the disease.

No one knows what causes Alzheimer’s disease. Genes, environment, lifestyle, and overall health may all play a role.

Stages of Alzheimer’s disease

The Alzheimer's Association identifies seven stages of Alzheimer's disease and says that each person moves through the disease stages in his or her own way. Knowing these stages helps doctors and family members make decisions about how to care for someone who has Alzheimer’s disease.

Stage 1: Normal function

In this stage, few signs of the disease may be apparent. But changes in the brain may have started.

Stage 2: Very mild cognitive decline

Symptoms at this stage include mild forgetfulness. This may seem like the mild forgetfulness that often comes with aging.

Stage 3: Mild cognitive decline

At this stage, a person may have problems:

  • Remembering a name

  • Recalling recent events

  • Remembering where he or she put a valuable object

  • Making plans

  • Staying organized

Stage 4: Moderate cognitive decline

At this stage, symptoms include:

  • Increasing difficulty remembering events

  • Difficulty with challenging math problems, such as counting backward from 100 by 7s

  • Problems managing money

  • Difficulty with planning complicated events, such as a dinner

  • Forgetting one’s own life story

  • Becoming moody or withdrawn

Stage 5: Moderately severe cognitive decline

At this stage, a person may:

  • Forget his or her address or phone number

  • Lose track of time and place

  • Need help choosing the right clothing

  • Have difficulty with easy math challenges, such as counting backward from 20 by 2s

Stage 6: Severe cognitive decline

At this stage, a person may:

  • Remember his or her name, but not details about his or her own life

  • Know that some people are familiar, but not remember their names

  • Forget the names of spouse or child

  • Need help with getting dressed

  • Need help with daily activities like brushing teeth

  • Have trouble with bathroom routines

  • Change his or her personality

  • Have problems with the way he or she sees the world, perhaps believing that caregivers are imposters or a threat

  • Have actions that he or she repeats, such as wringing the hands

  • Wander or get lost

Stage 7: Very severe cognitive decline

At this stage, a person loses many of his or her abilities. He or she may be able to say some words or phrases, but not carry on a conversation. He or she needs help with all activities.

More Information About Alzheimer's Disease from Johns Hopkins Medicine

Caretaker looks after a man with Alzheimer's disease

Alzheimer’s Disease: What You Need to Know as You Age

Take steps to prevent Alzheimer's, the most common form of dementia, and learn how to care for those suffering from it.

Read more.


The early signs of Alzheimer’s disease may not be obvious to anyone except the person with the disease and the people closest to him. Even then, the symptoms may be confused with normal changes that come with age.

To make a diagnosis, doctors usually do on an interview with you that uses several types of tests to find out how well your brain is working. These are often memory tests. They may seem like puzzles or word games. Your doctor might also take a medical history and order some tests to rule out other possible causes of memory loss or confusion. He or she might talk to your family members about symptoms they have noticed.


Treatment varies based on your age, overall health, medical history, symptoms, and preferences. Some medications can slow the progress of the disease in some people. These may work for a few months to several years.

Treatment might also be needed to help you with feelings of depression or anxiety. Sleep disorders can also be treated.

Caregivers and family members may benefit from therapy and support groups.

#TomorrowsDiscoveries: From Dysfunctional Cells to Disease – Dr. Rong Li

Dr. Li and her team investigate how cells consolidate their damaged proteins and prevent them from spreading freely, in order to understand how to better treat diseases such as Alzheimer’s and ALS. Another of their interests is how chromosomes are divided up when one cell becomes two. Learning more about how the process can go wrong could lend insight into cancer development.


Experts don’t know how to prevent Alzheimer’s disease. Most experts recommend a healthy, active lifestyle as the best way to protect your brain’s health.

Managing Alzheimer’s disease

People with Alzheimer’s disease need to follow a comprehensive treatment plan to protect their health. Even though you may have this disease, it is still important to take care of your physical health.

Finding help

You and your family may have many questions about living with Alzheimer’s disease. You can find information and support for yourself and your caregivers through the Alzheimer’s Association.

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