To facilitate research involving small molecules, the Department maintains a Bruker Avance III 500 MHz NMR spectrometer equipped with an autosampler. The automation is configured for a convenient queue up of common 1D (1H, 13C, 31P, DEPT, 1H with solvent suppression) and 2D (COSY, TOCSY, HSQC, HMBC, and NOESY) experiments.
The MS Facility comprises a Triple Quadrupole Mass Spectrometer, TSQ Vantage from Thermo Scientific and a nanoACQUITY UPLC system from Waters. The TSQ bears a HESI-II electrospray ionization source and this UPLC/MS system is well-suited for quantification and identification of small molecules as well as biomolecules.
These services are open to members of the JHU community. For training and further assistance, please contact the NMR/MS Facility Manager.
Shridhar Bhat, Ph.D.
NMR/MS Facility Manager
Pharmacology and Molecular Sciences
Johns Hopkins University School of Medicine
725 North Wolfe Street / WBSB-322
Learn more about the Biomolecular NMR Center, located on the Homewood Campus.