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Skull Base Giant Cell Tumor

What is a giant cell tumor?

Giant cell tumors, named for their extremely large cells, are rare bone tumors that usually affect the leg and arm bones but may be found in the skull. Most giant cell tumors are benign. They usually occur in people between the ages of 20 and 40.

Giant cell tumors may also be referred to as giant cell myeloma or osteoclastoma. Approximately 5% of giant cell tumors metastasize (spread) to the lungs.

Symptoms of a giant cell tumor:

Symptoms may include:

  • headache
  • vision changes
  • nerve pain

Diagnosis of a giant cell tumor:

In addition to a complete medical history and physical examination, diagnostic procedures for giant cell tumors may include X-ray, CT scan or MRI to determine the size and location of the tumor. Learn more about diagnosing skull base tumors.

Treatment for giant cell tumor:

Surgery, usually endonasal endoscopic surgery, is the most common treatment for giant cell tumors. Radiation therapy may be performed after surgery. Learn more about treatment for skull base tumors.

To make an appointment or request a consultation, contact the Johns Hopkins Skull Base Tumor Center at 410-614-0585.


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