Research and Clinical Trials

Research publications

Microsurgical clipping and endovascular coiling of intracranial aneurysms: a critical review of the literature (abstract)
Neurosurgery, 2008

Validation of an aneurysmal subarachnoid hemorrhage grading scale in 1532 consecutive patients (abstract)
Neurosurgery, 2008 

Orthogonal interlocking tandem clipping technique for the reconstruction of complex middle cerebral artery aneurysms (abstract)
Neurosurgery, 2006

 Intracranial aneurysms in the pediatric population: case series and literature review (abstract)
Surgical Neurology, 2005

Craniotomy for Treatment of Unruptured Aneurysms Is Not Associated With Long-Term Cognitive Dysfunction
Stroke, 2003

Microsurgical fenestration of the lamina terminalis reduces the incidence of shunt-dependent hydrocephalus after aneurysmal subarachnoid hemorrhage (abstract)
Neurosurgery, 2002

Routine intraoperative angiography during aneurysm surgery
Journal of Neurosurgery, 2002

Contralateral approaches to bilateral cerebral aneurysms: a microsurgical anatomical study (abstract)
Journal of Neurosurgery, 1997

A new subarachnoid hemorrhage grading system based on the Glasgow Coma Scale: a comparison with the Hunt and Hess and World Federation of Neurological Surgeons Scales in a clinical series(abstract)
Neurosurgery, 1997

Simple technique for intraoperative angiographic localization of small vascular lesions (abstract)
Neurosurgery, 2010

Vasospasm after subarachnoid hemorrhage in haptoglobin 2-2 mice can be prevented with a glutathione peroxidase mimetic
Journal of Clinical Neuroscience, 2010

Intra-Aortic Balloon Pump Counterpulsation in the Setting of Subarachnoid Hemorrhage, Cerebral Vasospasm, and Neurogenic Stress Cardiomyopathy. Case Report and Review of the Literature  
Neurocritical Care, 2010

Thrombosis and subsequent recanalization of a ruptured intracranial aneurysm in 2 children, demonstrating the value of repeating catheter angiography after an initial negative study (abstract) 
Journal of Neurosurgery Pediatrics, 2010

Intraoperative indocyanine green angiography for obliteration of a spinal dural arteriovenous fistula (abstract)
Journal of Neurosurgery Spine, 2009

Controlled delivery of nitric oxide inhibits leukocyte migration and prevents vasospasm in haptoglobin 2-2 mice after subarachnoid hemorrhage (abstract)
Neurosurgery, 2009

Inaccuracy of the administrative database: comparative analysis of two databases for the diagnosis and treatment of intracranial aneurysms (abstract)
Neurosurgery, 2009

Simvastatin for the prevention of symptomatic cerebral vasospasm following aneurysmal subarachnoid hemorrhage: a single-institution prospective cohort study (abstract)
Journal of Neurosurgery, 2009 

Middle cerebral artery branch occlusion mimicking a saccular aneurysm on 3D digital subtraction angiography (abstract)
Journal of Neurosurgery, 2008

Limitations of Magnetic Resonance Imaging and Magnetic Resonance Angiography in the diagnosis of intracranial aneurysms (abstract)
Neurosurgery, 2008

Frontozygomatic titanium cranioplasty in frontosphenotemporal ("pterional") craniotomy (abstract)
Neurosurgery, 2008 

Persistent perioperative hyperglycemia as an independent predictor of poor outcome after aneurysmal subarachnoid hemorrhage (abstract)
Journal of Neurosurgery, 2007

Haptoglobin 2-2 Genotype Determines Chronic Vasospasm After Experimental Subarachnoid Hemorrhage
Stroke, 2007

Delayed cerebral vasospasm secondary to bacterial meningitis after lumbosacral spinal surgery: case report
Neurosurgery, 2007

Safety of Cerebral Digital Subtraction Angiography in Children. Complication Rate Analysis in 241 Consecutive Diagnostic Angiograms
Stroke, 2006

Acute subdural hematoma caused by an unruptured, thrombosed giant intracavernous aneurysm (abstract)
Neurocritical Care, 2006

Systemic administration of simvastatin after the onset of experimental subarachnoid hemorrhage attenuates cerebral vasospasm (abstract)
Neurosurgery, 2006  

Aneurysmal rupture without subarachnoid hemorrhage: case series and literature review (abstract)
Neurosurgery, 2005

Long term visual and neurological prognosis in patients with treated and untreated cavernous sinus aneurysms (abstract)
Journal of Neurology, Neurosurgery, and Psychiatry, 2004 

De Novo Aneurysm Formation 6 and 22 Months after Initial Presentation in Two Patients
American Journal of Neuroradiology, 2003

Inhibition of vasospasm with lymphocyte function-associated antigen-1 monoclonal antibody in a femoral artery model in rats (abstract)
Journal of Neurosurgery, 2002

Symptomatic vasospasm diagnosis after subarachnoid hemorrhage: evaluation of transcranial Doppler ultrasound and cerebral angiography as related to compromised vascular distribution (abstract)
Critical Care Medicine, 2002

Cocaine Use Is an Independent Risk Factor for Cerebral Vasospasm After Aneurysmal Subarachnoid Hemorrhage
Stroke, 2001

Risk factors for subarachnoid hemorrhage
Neurosurgery, 2001

Early predictors of outcome in patients receiving hypervolemic and hypertensive therapy for symptomatic vasospasm after subarachnoid hemorrhage
Critical Care Medicine, 2000   

Ischemic events associated with unruptured intracranial aneurysms: multicenter clinical study and review of the literature (abstract)
Neurosurgery, 2000

Marfan Syndrome Is Not Associated With Intracranial Aneurysms
Stroke, 1999 

Administration of hypertonic (3%) sodium chloride/acetate in hyponatremic patients with symptomatic vasospasm following subarachnoid hemorrhage (abstract)
Journal of Neurosurgical Anesthesiology, 1999

Inhibition of experimental vasospasm with anti-intercellular adhesion molecule-1 monoclonal antibody in rats
Stroke, 1997

Endothelial cell expression of intercellular adhesion molecule-1 (ICAM-1) in experimental post-hemorrhagic vasospasm (abstract)
Neurosurgery, 1997

Current clinical trials

Visit clinicaltrials.gov for a complete listing of clinical trials available at Johns Hopkins.

To request an appointment or refer a patient, please contact the Johns Hopkins Aneurysm Center at 410-614-1533.