The Transgenic and Neurobehavior Core will be a shared resource of the Parkinson's Disease Research Center and will play a central role in our investigations in the pathogenesis of Parkinson's disease. It will generated and maintain breeding colonies of transgenic and gene-targeted mouse lines and it will provide cohorts of transgenic and gene-targeted mice for studies proposed in Project 1, Project 2, and Project 3 of the Center grant. It will assist in the generation of new transgenic and gene-targeted mice. It will establish C57BI6 congenic lines of transgenic mice used throughout the study. It will assist with methods to examine motor and clinical deficits in mouse models of Parkinson's disease.
Han Seok Ko, PhD (Principal Investigator)