Purpose: To evaluate effectiveness of various HIV-drug (antiretroviral) regimens.
Criteria: Must be getting ready to change or start HIV-drug cocktail, and your doctor is aware of your interest in this study.
This clinical trial ended January 2012
Purpose: To evaluate if Minocycline helps to improve cognitive impairment.
- Stable HIV-drug (antiretroviral) cocktail for at least 16 weeks.
- Trouble remembering things, trouble doing simple tasks quickly.
- An HIV-drug regimen with Reyataz (Atazanavir) is now allowed
NOTE: Closed for enrollment; clinical trial ended 2010
NIH Study Report
A Randomized, Rater-Blinder Study to Explore the Effect of Mefloquine in Subjects with Progressive Multifocal Leukoencephalopathy (PML)
Purpose: To explore whether Mefloquine can delay of stop progression of PML measured by JCV DNA levels in CSF, and to explore whether Mefloquine can delay or stop progression of PML based on Neurological deterioration, MRI measures of the brain lesion evolution or the formation of new lesions, and mortality.
This clinical trial ended September, 2010