This course is a newly devised graduate course in the School of Medicine, sponsored by the JHU NIMH Center to provide an overview of Therapeutic Development for neurological diseases.
The course will focus on preclinical drug development and will include the necessary phases involved in this process, including Idea Conception, Exploratory Research, Medicinal Chemistry, Drug Screening, Protection of Intellectual Property, Development of Surrogate Markers and the role of Regulatory Affairs. This will be followed up with specific examples of drug development for specific neurodegenerative disorders including Parkinson’s Disease, Alzheimer’s Disease, Huntington’s Disease, ALS, Peripheral Neuropathy, and HIV-associated Neurocognitive Disorders (HAND).
The course Director is Joseph Steiner, Ph.D., and Norman Haughey, Ph.D. is Co-director. Expert guest lecturers are scheduled each week.
COURSE FORMAT: 1 hour TAPED LECTURES and 1 hour LIVE SUMMARY or JOURNAL CLUB.
For more information contact Joseph Steiner at firstname.lastname@example.org or Norman Haughey at email@example.com.
Previous Neurotherapeutics lectures included:
- Exploratory Research/Target Validation
Lecturer: Dr. Paul Jackson, J&J Pharmaceutical Inc.
- Drug Screening
Lecturer: Dr. Camilo Rojas, BSI
- Medicinal Chemistry Lead ID/Optimization
Lecturer: Dr. Dana Ferraris, BSI
- In Vivo Proof of Concept: Animal Models
Lecturers: Dr. Douglas Kerr, JHU, Rita Sattler, JHU
- Biopharmaceutics: Pharmacokinetics
Lecturer: Dr. Norman Haughey, JHU
- BBB permeability
Lecturer: Dr. Monique Stins, JHU
- Regulatory Affairs-pre-IND through NDA
Lecturer: Dr. Gerald Dal Pan, FDA
- Human Clinical Studies
Lecturer: Dr. Justin McArthur, JHU
- Surrogate Markers
Lecturer: Dr. Avi Nath, JHU
- Drug Development for Parkinson’s Disease
Lecturer: Dr. Ted Dawson, JHU
- Drug Development for ALS
Lecturer: Dr. Jeff Rothstein, JHU
- Drug Development for Alzheimer’s Disease
Lecturer: Dr. Don Price, JHU
- Drug Development for Huntington’s Disease
Lecturer: Dr. Chris Ross, JHU
- Drug Development for HIV-associated cognitive disorders
Lecturer: Dr. Joe Steiner, JHU
- Drug Development for Peripheral Neuropathy
Lecturer: Dr. Ahmet Hoke, JHU
- Biologics Development
Lecturer: Dr. Susan Goelz, Biogen-Idec
- Neural Instruments
Lecturer: Dr. Nitish Thakor, JHU
- Stem Cells as Therapeutics
Lecturer: Dr. Hongjun Song, JHU