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Studying fruit flies, whose sleep is remarkably similar to that in people, Johns Hopkins researchers say they’ve identified brain cells that are responsible for why delaying bedtime creates chronic sleepiness.
Alan R. Cohen, M.D., has been named the new chief of Johns Hopkins Medicine’s Division of Pediatric Neurosurgery and holder of the Benjamin S. Carson Sr., M.D., and Dr. Evelyn Spiro, R.N., Professorship in Pediatric Neurosurgery.
Argye Hillis, M.D., a professor of neurology at the Johns Hopkins University School of Medicine, is serving on a team of researchers from several institutions who will use an $11 million grant from the National Institutes of Health to study stroke recovery.
Results of a small study of people with tingling pain in their hands and feet have added to evidence that so-called prediabetes is more damaging to motor nerves than once believed, in a report on the study published online in JAMA Neurology on April 11.
Johns Hopkins scientists report they have developed an antibody against a specific cellular gateway that suppresses lung tumor cell growth and breast cancer metastasis in transplanted tumor experiments in mice, according to a new study published in the February issue of Nature Communications.
In a small clinical study with an anticancer drug that halts blood vessel growth, a handful of people with neurofibromatosis type 2 (NF2) and hearing loss had restoration of hearing. Results of the collaborative study by researchers at Johns Hopkins Medicine, the National Institutes of Health and Massachusetts General Hospital were described online March 14 in the Journal of Clinical Oncology.
Working with lab-grown human stem cells, a team of researchers suspect they have discovered how the Zika virus probably causes microcephaly in fetuses. The virus selectively infects cells that form the brain’s cortex, or outer layer, making them more likely to die and less likely to divide normally and make new brain cells.
In a small, placebo-controlled clinical trial, Johns Hopkins physicians report that the antidepressant paroxetine modestly improves decision-making and reaction time, and suppresses inflammation in people with HIV-associated cognitive impairment.
Reporting on the results of a phase III international clinical trial, Johns Hopkins Medicine physicians say use of a cardiac clot-busting drug to treat strokes that cause brain bleeding safely decreased the death rate in patients by 10 percent, compared to a control group receiving saline.
Physicians and biomedical engineers from Johns Hopkins report what they believe is the first successful effort to wiggle fingers individually and independently of each other using a mind-controlled artificial “arm” to control the movement.
Using mice whose front paws were still partly disabled after an initial induced stroke, Johns Hopkins researchers report that inducing a second stroke nearby in their brains let them “rehab” the animals to successfully grab food pellets with those paws at pre-stroke efficiency.
Taking a high dose of vitamin D3 is safe for people with multiple sclerosis and may help regulate the body’s hyperactive immune response, according to a pilot study published by Johns Hopkins physicians in the Dec. 30 online issue of Neurology, the medical journal of the American Academy of Neurology.
Scientists have long known that when sounds are faint or objects are seen through fog in the distance, repetition of these weak or ambiguous sensory “inputs” can result in different perceptions inside the same brain. Now the results of new research have identified brain processes in mice that may help explain how those differences happen.
Johns Hopkins researchers have developed a method to efficiently turn human stem cells into retinal ganglion cells, the type of nerve cells located within the retina that transmit visual signals from the eye to the brain.
Before the fluid of the middle ear drains and sound waves penetrate for the first time, the inner ear cells of newborn rodents practice for their big debut. Researchers at Johns Hopkins report they have figured out the molecular chain of events that enables the cells to make “sounds” on their own, essentially “practicing” their ability to process sounds in the world around them.
Richard T. Johnson, an internationally renowned Johns Hopkins neurologist who is credited with inventing the field of neurovirology — the study of viruses that infect the nervous system — died at The Johns Hopkins Hospital on November 22 of pneumonia.
As we age or develop neurodegenerative diseases such as Alzheimer's, our brain cells may not produce sufficient energy to remain fully functional. Researchers discovered that an enzyme called SIRT3 that is located in mitochondria — the cell's powerhouse — may protect mice brains against the kinds of stresses believed to contribute to energy loss. Furthermore, mice that ran on a wheel increased their levels of this protective enzyme.
A study led by Johns Hopkins Medicine researchers suggests that awakening several times throughout the night is more detrimental to people’s positive moods than getting the same shortened amount of sleep without interruption.
Peter Calabresi, M.D., professor of neurology and director of the Johns Hopkins Multiple Sclerosis Center, was part of the team selected to receive the 2015 Barancik Prize for Innovation in Multiple Sclerosis Research awarded by the National Multiple Sclerosis Society. The prize recognizes innovation and originality in MS research, with emphasis on the potential to lead to treatments and a cure for MS.
People with Parkinson’s disease (PD) tend to slow down and decrease the intensity of their movements even though many retain the ability to move quickly and forcefully. Now, scientists report evidence that the slowdown likely arises from the brain’s “cost/benefit analysis,” which gets skewed by the loss of dopamine in people with PD. In addition, their small study demonstrated that noninvasive electrical stimulation of the brain temporarily improved some patients’ motor symptoms.
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