Skip Navigation
Search Menu
Neurology and Neurosurgery

In This Section      
Print This Page

Animal Study

Another way to learn about the underlying biological mechanism of primary motor stereotypies is to study animals that exhibit spontaneous repetitive movements. We’re currently conducting an animal study that examines the brain chemistry of deer mice that have inherited involuntary stereotypic jumping and somersault movements.

High jumper deer mouse

The deer mouse (Perromyscus maniculatus) raised in standard laboratory caging develops high rates of spontaneous stereotyped behaviors such as jumping, rearing and flipping. Here is an example of repetitive jumping.

High Jumper deer mouse - Backflipper

Here a deer mouse raised in the lab exhibits spontaneous stereotyped backward flipping behavior.

Our goal is to identify differences in brain chemicals (neurotransmitters) between animals with frequent and infrequent motor stereotypies. Understanding the underlying biological mechanisms could lead to the development of potential pharmacological treatments.

Pharmacotherapy

Future studies are planned to test specific, yet-to-be-determined drugs. Based on our animal studies, a pharmacotherapy treatment may be developed for patients with motor stereotypies disorder.

«« back to Research Studies

Request an Appointment

Maryland Patients

Pediatric Neurology: 410-955-4259

 

Traveling for Care?

Whether you're crossing the country or the globe, we make it easy to access world-class care at Johns Hopkins.

Outside of Maryland (toll free)
410-464-6713

Request an Appointment
Medical Concierge Services

International Patients
+1-410-502-7683

Request an Appointment
Medical Concierge Services

 
blue suitcase