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Clinical Trials

Currently Enrolling Research Studies in Movement Disorders

Your participation will allow you to have first hand experience with developing new medical treatments, which may be beneficial to many individuals in the future. The current methods that are used to treat neurologic disorders are available because of others who have volunteered their time and energy in the past. Clinical trial information is excerpted from

Parkinson’s DiseaseParkinson Progression Markers Initiative (PPMI) - Genetic CohortIdentify genetic links to PD and learn how the LRRK2 mutation affects certain populations of people. (Part of the Michael J.Fox Foundation Parkinson’s Progression Markers Initiative)1.) Individuals diagnosed with PD and are of Ashkenazi Jewish decent
2.) Individuals without PD who are of Ashkenazi Jewish decent AND have a first degree relative with PD. PI: Zoltan Mari, M.D. (NA_00039232)
Arita McCoy, R.N., B.S.N.
(410) 955-2954
Parkinson’s DiseaseNational Parkinson Foundation Patient RegistryDevelop quality care standards for PDAll PD patients and carepartners
PI: Zoltan Mari, M.D. (NA_00036863)
Becky Dunlop, R.N., B.S.N.
(410) 955-8795

Bailey Vernon, M.P.H.
(410) 616-2811
Parkinson's DiseaseUdall Center Longitudinal StudyExamine the relationship between the clinical symptoms of PD and the disease process in brain tissure (participation includes eventual brain donation)Individuals diagnosed with PD or atypical PD and those without a neurological diagnosis
Liana Rosenthall, M.D.
Catherine Bakker (410) 616-2814
Parkinson's DiseaseUdall Center Brain Donation ProgramExamine the pathological changes in brain tissue of those diagnosed with PD or related disorders as compared to controlsIndividuals diagnosed with PD or atypical PD and those without a neurological diagnosis
Liana Rosenthall, M.D.
Catherine Bakker (410) 616-2814
Parkinson's DiseaseAdamas 302 (blinded) and 304 (placebo control)Determine safety and effectiveness of new extended release formulation of amantadine (amantadine HCL) to treat dyskinesiaIndividuals with PD who have untreated dyskinesia
Kelly Mills, MD (NA_00056431) (NA_00056432)
Becky Dunlop, R.N.
(410) 955-8795
Parkinson’s DiseaseMARK-PDFind biomarkers to improve diagnosis and treatment of people with PDIndividuals without PD
PI: Liana Rosenthal, M.D. (NA_00031749)
Nadine Yoritomo, R.N., B.S.N., C.C.R.P.
(410) 616-2822
Parkinson's DiseaseAnxiety in Parkinson's One-day visit to assess anxiety symptoms in PDAll individuals diagnosed with PD
Reza Shadmehr, PhD (NA_00081426)
Yousef Salimpour, Ph.D.
(410) 614-3424
Parkinson's DiseaseSTEADY-PDDetermine if isradipine alters disease courseIndividuals with PD who are not greated
PI: Zoltan Mari, M.D. (NA_00038373)
Becky Dunlop, R.N.
(410) 955-8795
DystoniaDystonia CoalitionDevelop better understanding of dystoniaAdults 18 and older with primary dystonia
PI: Zoltan Mari, M.D. (NA_00074297)
Becky Dunlop, R.N.
(410) 955-8795
All patientsLongitudinal Study of Parkinson's Disease and Related DisordersMaintain a database of people interested in future studiesAll patients and caregivers
PI: Liana Rosenthal, M.D. (NA_00032761)
Vanessa Johnson, B.S.
(410) 614-1480
Parkinson's DiseaseTranscranial Direct Current StimulationTest the therapeutic relevance of non-invasive brain stimulation for improving motor symptomsDiagnosed PD patients
PI: Reza Shadmehr, Ph.D. (NA_00081426)
Yousef Salimpour, Ph.D.
(410) 614-3424
Parkinson's DiseaseMysticolInvestigate the efficacy of MYOBLOC (Botulinum toxin type B) injection in the treatment of sialorrhea (drooling or excessive salivation)Adults 18 and older with untreated excessive salivation in the last 3 months due to any cause
PI: Zoltan Mari, M.D. (NA_00084484)
Becky Dunlop, R.N.
(410) 955-8795

Movement Disorder Symposium

Our November 8 Symposium was a great success, with the latest in the management of movement disorders from experts at Johns Hopkins Medicine and other health organizations in Maryland. Here's a recap.

PFNCA Annual Symposium:

Dr. Mari discusses past and present Parkinson’s Disease therapies

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