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Upper Aerodigestive Cancer

Smoking continues to be a leading cause of cancer. Investigators in the Upper Aerodigestive Cancer Program focus their attention on cancers most directly linked to tobacco use, including lung, head and neck, and esophageal cancers. The last five years has seen great progress in laboratory research and marked increase in clinical research with the development of new therapeutic strategies. Our scientists have made important advances in deciphering the role of epigenetics in altering gene expression and identified gene pathways involved in the growth and progression of these cancers. Investigators continue to be focused on identifying environmental risk factors, molecular changes that initiate cancers in the upper aerodigestive tract, and developing new strategies to prevent and treat these cancers. Program Leaders are Charles Rudin, M.D., Ph.D., and David Sidransky, M.D.

The Johns Hopkins Head and Neck Cancer SPORE

SPORE stands for Specialized Program of Research Excellence and the funds are one of the most sought-after by researchers nationwide because they focus on turning research into results – linking basic science discoveries with new tests and therapies that help patients. Our SPORE will speed research on new treatments for head and neck cancers.

Physician Scientists

Photo of Dr. Douglas Wilmot Ball, M.D.

Ball, Douglas Wilmot, M.D.

Associate Professor of Medicine
Associate Professor of Oncology
 
Photo of Dr. Julie Renee Brahmer, M.D.

Brahmer, Julie Renee, M.D.

Associate Professor of Oncology
Co-Director of the Upper Aerodigestive Department within the Bloomberg~Kimmel Institute for Cancer Immunotherapy
Director, Thoracic Oncology
 
Photo of Dr. Malcolm V Brock, M.D.

Brock, Malcolm V, M.D.

Professor of Surgery
Professor of Oncology
Medical Director, Center for Sweat Disorders
Director of Clinical and Translational Research in Thoracic Surgery
 
Photo of Dr. David S Ettinger, M.D.

Ettinger, David S, M.D.

Professor of Oncology
Professor of Gynecology and Obstetrics
Professor of Medicine
Professor of Otolaryngology - Head and Neck Surgery
Professor of Radiation Oncology and Molecular Radiation Sciences
Alex Grass Professor in Oncology
 
Photo of Dr. Arlene Forastiere, M.D.

Forastiere, Arlene, M.D.

Professor of Oncology
Professor of Otolaryngology - Head and Neck Surgery
Professor of Radiation Oncology and Molecular Radiation Sciences
 
Photo of Dr. Edward W Gabrielson, M.D.

Gabrielson, Edward W, M.D.

Professor of Pathology
Professor of Oncology
Attending Pathologist, Johns Hopkins Hospital
Attending Pathologist, Johns Hopkins Bayview Medical Center
 
Photo of Dr. Christine Lee Hann, M.D., Ph.D.

Hann, Christine Lee, M.D., Ph.D.

Assistant Professor of Oncology
 
Photo of Dr. Lawrence Richard Kleinberg, M.D.

Kleinberg, Lawrence Richard, M.D.

Associate Professor of Radiation Oncology and Molecular Radiation Sciences
Associate Professor of Neurosurgery
Associate Professor of Oncology
 
Photo of Dr. Wayne M Koch, M.D.

Koch, Wayne M, M.D.

Professor of Otolaryngology - Head and Neck Surgery
Professor of Oncology
Director, Johns Hopkins Head and Neck Cancer Center
 
Photo of Dr. William Henry Westra, M.D.

Westra, William Henry, M.D.

Professor of Pathology
Associate Professor of Dermatology
Professor of Oncology
Professor of Otolaryngology - Head and Neck Surgery
Director, Head and Neck Pathology Laboratory
 
Photo of Dr. Michael Mingzhao Xing, M.D., Ph.D.

Xing, Michael Mingzhao, M.D., Ph.D.

Professor of Medicine
Professor of Oncology
Professor of Pathology
 
Photo of Dr. Stephen Clyde Yang, M.D.

Yang, Stephen Clyde, M.D.

Professor of Surgery
Professor of Oncology
Associate Vice Chair for Faculty Development
The Arthur B. and Patricia B. Modell Professor in Thoracic Surgery
 
Photo of Dr. Martha A Zeiger, M.D.

Zeiger, Martha A, M.D.

Professor of Surgery
Professor of Oncology
Associate Dean for Postdoctoral Affairs
Associate Vice Chair of Research for Department of Surgery
Co-Director, Basic and Translational Research
Chief, Endocrine Surgery
 

Laboratory Scientists

Baylin, Stephen, M.D
Biswal, Shyam, Ph.D.
Califano, Joseph, M.D.
Goodman, Steven, M.D., Ph.D.
Nelkin, Barry, Ph.D.
Sidransky, David, M.D.