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Dr. David Holtgrave


Department Chair 

Departmental Affiliation
Health, Behavior and Society
Joint Departmental Affiliations
Health Policy and Management

Research Summary

Dr. Holtgrave's research has focused on the effectiveness and cost-effectiveness of a variety of HIV prevention interventions, and the relationship of the findings of these studies to HIV prevention policy making. He has served on an Institute of Medicine panel charged with recommending methods to improve the public financing and delivery of HIV care in the United States.

Dr. Holtgrave has also investigated the relationship between social capital measures, infectious disease rates, and risk behavior prevalence. He has worked extensively on HIV prevention community planning, and has served as a member of the Wisconsin HIV Prevention Community Planning group.

Journal Citations

Holtgrave, D.R.; Wunderink, K.A.; Vallone, D.M.; Healton, C.G. Cost-utility analysis of the National truth campaign to prevent youth smoking. Am J Prev Med. 2009 May;36(5):385-388.

Farnham, P.G.; Holtgrave, D.R.; Sansom, S.L.; Hall, H.I. Medical costs averted by HIV prevention efforts in the United States, 1991-2006. J Acquir Immune Defic Syndr. 2010 Aug 15;54(5):565-567.

Holtgrave, D.R. On the epidemiologic and economic importance of the National AIDS Strategy for the United States. J Acquir Immune Defic Syndr. 2010 Oct 1;55(2):139-142.

Villanti, A.C.; McKay, H.S.; Abrams, D.B.; Holtgrave, D.R.; Bowie, J.V. Smoking-cessation interventions for U.S. Young adults: a systematic review. Am J Prev Med. 2010 Dec;39(6):564-574.

Holtgrave DR, Kates J. HIV incidence and CDC's HIV prevention budget: An explatory correlational analysis. American Journal of Preventive Medicine. Epub ahead of print, 2006 Dec.

Holtgrave DR, Pinkerton SD. Can increasing awareness of HIV seropositivity reduce HIV incidence by 50%? Journal of Acquired Immune Deficiency Syndromes. Epub ahead of print, 2006 Dec.

Holtgrave DR. Resilient organizations, mobilized communities, and evidence-based HIV prevention programs: Examining the influence of a national investment in HIV/AIDS capacity building. Journal of Public Health Management and Practice. 13(Supplement 1): S1-S4, 2007 Jan.

Holtgrave DR. Curran JW. What Works, and What Remains to Be Done, in HIV Prevention in the

United States. Annual Review of Public Health. 27:261-275, 2006.

Holtgrave DR. Causes of the Decline in AIDS Deaths, United States, 1995-2002: Prevention, Treatment or Both? International Journal of STD & AIDS. 16(12)777-781, 2005 Dec.

Holtgrave DR. Crosby RA. Is Social Capital a Protective Factor Against Obesity and Diabetes? Findings from an Exploratory Study. Annals of Epidemiology. 16(5):406-408, 2006 May.

Holtgrave DR. Using Economic Threshold Analysis to Determine the Intensity of HIV Prevention Services for HIV Seropositive Persons. AIDS. 19(17):2025-2039, 2005 Nov.

Crosby RA, Holtgrave DR. Will Sexual Risk Behavior Increase After Being Vaccinated For AIDS? International Journal of STD & AIDS. 17(3):180-184, 2006 Mar.

Salazar L, Crosby RA, Holtgrave DR, Frew P, Peterson J. Issues related to gay and bisexual men's acceptance of a future AIDS vaccine. International Journal of STD & AIDS. 16(8):546-548, 2005 Aug.

Crosby RA, Holtgrave DR. The protective value of social capital against teen pregnancy: A state-level analysis. Journal of Adolescent Health. 38(5): 556-559, 2006 May.

Holtgrave DR. Anderson T. Utilizing HIV transmission rates to assist in prioritizing HIV prevention services. International Journal of STD & AIDS. 15(12):789-92, 2004 Dec.

Holtgrave DR. HIV-AIDS in the US: Three policy issues. Evidence-Based Healthcare & Public Health. 9:4-6, 2005.

Holtgrave DR. HIV prevention, cost-utility analysis, and race/ethnicity: Methodological considerations and recommendations. Medical Decision Making 24(2):181-191, 2004.

Holtgrave DR. A proposed format for tracking the Centers for Disease Control and Prevention's national HIV prevention goal. Journal of Public Health Management & Practice. 11(1):4-6, 2005 Jan-Feb.

Crosby RA. Holtgrave DR. Bryant L. Frew PM. Correlates of negative intent to receive an AIDS vaccine: an exploratory study. International Journal of STD & AIDS. 15(8):552-7, 2004 Aug.

Crosby RA. Holtgrave DR. Bryant L. Frew PM. Factors associated with the acceptance of an AIDS vaccine: an exploratory study. Preventive Medicine. 39(4):804-8, 2004 Oct.

Holtgrave DR. Estimation of annual HIV transmission rates in the United States, 1978-2000. Journal of Acquired Immune Deficiency Syndromes: JAIDS. 35(1):89-92, 2004 Jan 1.

Holtgrave DR. Crosby RA. Social determinants of tuberculosis case rates in the United States. American Journal of Preventive Medicine. 26(2):159-62, 2004 Feb.

Holtgrave DR. The role of quantitative policy analysis in HIV prevention technology transfer. Public Health Reports. 119(1):19-22, 2004 Jan-Feb.

Holtgrave DR. Behavioral approaches to HIV prevention. Emory International Law Review, 2003, 17, 547-559.

Trentacoste ND. Holtgrave DR. Collins C. Abdul-Quader A. Disseminating effective behavioral interventions for HIV prevention: a cost analysis of a risk-reduction intervention for drug users. Journal of Public Health Management & Practice. 10(2):130-9, 2004 Mar-Apr.

Mettey A. Crosby R. DiClemente RJ. Holtgrave DR. Associations between internet sex seeking and STI associated risk behaviours among men who have sex with men. Sexually Transmitted Infections. 79(6):466-8, 2003 Dec.

Crosby RA. Holtgrave DR. DiClemente RJ. Wingood GM, Gayle JA. Social capital as a predictor of adolescents' sexual risk behavior: a state-level exploratory study. AIDS & Behavior. 7(3):245-52, 2003 Sep.

Ekwueme DU. Pinkerton SD. Holtgrave DR. Branson BM. Cost comparison of three HIV counseling and testing technologies. American Journal of Preventive Medicine. 25(2):112-21, 2003 Aug.


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