Skip Navigation
Print This Page
Share this page: More

High Dose Cyclophosphamide

Physician-scientists at Johns Hopkins have developed a treatment program using high doses of the chemotherapy drug cyclophosphamide (trade name: cytoxan), without bone marrow transplantation, to “re-boot” the immune system and achieve long-lasting, complete remissions in some patients with severe aplastic anemia, multiple sclerosis, and other autoimmune disorders. The drug can rid the body of the cells that cause aplastic anemia without destroying key blood and bone marrow-forming stem cells.

Dr. Robert Brodsky, director of the Division of Hematology, and his colleagues in neurology and rheumatology are applying this approach in other severe autoimmune disorders, including aplastic anemia, scleroderma, myasthenia gravis, multiple sclerosis, and other autoimmune hematologic disorders.


Read Our Blogs
Cancer Matters: timely topics
Our Cancer: for caregivers

Traveling for care?

blue suitcase

Whether crossing the country or the globe, we make it easy to access world-class care at Johns Hopkins.

Maryland 410-955-5222
U.S. 410-955-5222
International +1-410-614-6424



© The Johns Hopkins University, The Johns Hopkins Hospital, and Johns Hopkins Health System. All rights reserved.

Privacy Policy and Disclaimer