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Key Publications

Liang, G., Klose, R. J., Gardner, K. E., and Zhang, Y. (2007). Yeast Jhd2 is an H3K4 tri-methyl demethylase. Nature Stru. Mol. Biol. 14, 243-245.  PubMed Link

Klose, R. J., Yan, Q., Tothova, Z., Yamane, K., Erdjument-Bromage, H., Tempst, P., Gilliland, D. G., Zhang, Y., Kaelin, W. G. (2007). The retinoblastoma binding protein RBP2 is an H3K4 demethylase. Cell 128, 889-900.  PubMed Link

Lee, N., Zhang, J., Klose, R. J., Erdjument-Bromage, H., Tempst, P., Jones, R. S., and Zhang, Y. (2007). The trithorax group protein Lid is a trimethyl-H3K4 demethylase. Nature Stru. Mol. Biol. 14, 341-343.  PubMed Link

Yamane, K., Klose, R. J., Fabrizio, L. A., Erdjument-Bromage, H., Taylor-Papadimitriou, J., Tempst, P., and Zhang, Y. (2007). PLU-1 is an H3K4 demethylase involved in transcriptional repression and breast cancer cell proliferation. Mol Cell 25, 801-812.  PubMed Link

Klose, R. J., Gardner, K. E., Liang, G., Erdjument-Bromage, H., Tempst, P., and Zhang, Y. (2007). Demethylation of histone H3K36 and H3K9 by Rph1: a vestige of an H3K9 methylation system in Saccharomyces cerevisiae? Mol Cell Biol. 27, 3951-3961.  PubMed Link

Fang, J., Hogan, G. J., Liang, G., Lieb, J. D., and Zhang, Y. (2007). The Saccharomyces cerevisiae histone demethylase Jhd1 fine-tunes the distribution of H3K36me2. Mol Cell Biol. 27, 5055-5065.  PubMed Link

Okada, Y., Scott, G., Ray, M. K., Mishina, Y., Zhang, Y. (2007). Histone demethylase Jhdm2a is critical for Tnp1 and Prm1 transcription and spermatogenesis. Nature 450, 119-123.  PubMed Link

Cao, R., Wang, H., He, J., Erdjument-Bromage, H., Tempst, P., and Zhang, Y. (2008). Role of hPHF1 in H3K27 methylation and Hox gene silencing. Mol Cell Biol. 28, 1862-1872.  PubMed Link