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Geraldine Seydoux

Geraldine Seydoux

Understanding embryonic development

Geraldine Seydoux is a developmental biologist who studies how early embryos develop into complex asymmetric structures comprising many cell types. Geraldine uses the transparent worm C. elegans as a model system and has developed methods to film and measure protein dynamics in live embryos.  Her lab has found that the C. elegans embryo becomes polarized after fertilization when microtubules associated with the sperm come in contact with the plasma membrane.  Using genetics, biochemistry and quantitative microscopy, the Seydoux lab is investigating how interactions between microtubules and the membrane cause complex protein networks to “self-organize” and polarize the entire embryo.

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