| Summary of Trial: | The study is designed to contrast the relative efficacy of Carotid Artery Stenting (CAS) versus Carotid Endarterectomy (CEA) in preventing stroke, myocardial infarction, and death during a 30-day peri-procedural period, and stroke ipsilateral to the study artery over the 12 months follow-up period in patients with symptomatic and asymptomatic extracranial carotid stenosis. |
| Principal Investigator: | Mahmoud B Malas, M.D., MHS, FACS |
| Study Coordinator: | Umair Qazi, M.D., MPH |
| Study Long Title: | Carotid Revascularization Endarterectomy vs. Stenting Trial |
| Study Short Title: | CREST |
| JHU IRB Number: | NA_00001028 |
| Funding Source: | National Institute of Neurological Disorders and Stroke (NINDS) National Institutes of Health (NIH) |
| Clinical Trial Site: | The study enrolled a total of about 2500 randomized patients in multiple sites across the U.S. Enrollment is now closed. Patients are in follow-up. Important results are being published in several respected clinical journals. Johns Hopkins Bayview Medical Center 4940 Eastern Ave Baltimore MD 21224 |
| Start Date: | 2006 |
| Anticipated End Date: | 2016 |
| Compensation for Participating: | None |
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