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ARVD/C and Exercise

  • Judge DP and Chelko SP. Further Evidence of Harm from Exercise in ARVD/C. JACC 2015; 65(14): 1451-3.

  • Rojas A, Calkins H. Present understanding of the relationship between exercise and arrhythmogenic right ventricular dysplasia/cardiomyopathy. Trends Cardiovasc Med. 2015 Apr;25(3):181-188. doi: 10.1016/j.tcm.2014.10.007. Epub 2014 Oct 30. Review.

  • Sawant AC, Bhonsale A, te Riele AS, Tichnell C, Murray B, Russell SD, Tandri H, Tedford RJ, Judge DP, Calkins H, James CA. Exercise has a disproportionate role in the pathogenesis of arrhythmogenic right ventricular dysplasia/cardiomyopathy in patients without desmosomal mutations. J Am Heart Assoc. 2014 Dec;3(6):e001471.
  • Fabritz L, Fortmueller L, Vloumidi E, Sakhtivel S, Syeda F, Leube R, Kirchhof P, Krusche C. 11 arrhythmogenic right ventricular cardiomyopathy-like phenotype induced by endurance training and prevented by preload reduction in heterozygeous desmoglein-2 mutants. Heart. 2014 Jan;100 Suppl 1:A5. 

  •  Perrin MJ, Angaran P, Laksman Z, Zhang H, Porepa LF, Rutberg J, James C, Krahn AD, Judge DP, Calkins H, Gollob MH. Exercise testing in asymptomatic gene carriers exposes a latent electrical substrate of arrhythmogenic right ventricular cardiomyopathy. J Am Coll Cardiol. 2013 Nov 5;62(19):1772-9. 

  • James CA, Bhonsale A, Tichnell C, Murray B, Russell SD, Tandri H, Tedford RJ, Judge DP, Calkins H. Exercise increases age-related penetrance and arrhythmic risk in arrhythmogenic right ventricular dysplasia/cardiomyopathy-associated desmosomal mutation carriers. J Am Coll Cardiol. 2013 Oct 1;62(14):1290-7. 

  • Zorzi A, ElMaghawry M, Rigato I, Cardoso Bianchini F, Crespi Ponta G, Michieli P, Migliore F, Perazzolo Marra M, Bauce B, Basso C, Schiavon M, Thiene G, Iliceto S, Corrado D. Exercise-induced normalization of right precordial negative T waves in arrhythmogenic right ventricular cardiomyopathy. Am J Cardiol. 2013 Aug 1;112(3):411-5. 

  • Pelliccia A, Corrado D, Bjornstad HH, Panhuyzen-Goedkoop N, Urhausen A, Carre F, Anastasakis A, Vanhees L, Arbustini E, Priori S. Recommendations for participation in competitive sport and leisure-time physical activity in individauls with cardiomyopathies, myocarditis and pericarditis. Eur J Cardiovasc Prev Rehabil. 2006 Dec; 13(6):876-85. View abstract.
  • Kirchhof P, Fabritz L, Zwiener M, Witt H, Schafers M, Zellerhoff S, Paul M, Athai T, Hiller KH, Baba HA, Breithardt G, Ruiz P, Wichter T, Levkau B. Age- and training-dependent development of arrhythmogenic right ventricular cardiomyopathy in heterozygous plakoglobin-deficient mice. Circulation. 2006 Oct 24; 114 (17):1799-806. Read full article.
  • Maron BJ, Chaitman BR, Ackerman MJ, Bayes de Luna A, Corrado D, Crosson JE, Deal BJ, Driscoll DJ, Estes NA 3rd, Araujo CG, Liang DH, Mitten MJ, Myerburg RJ, Pelliccia A, Thompson PD, Towbin JA, Van Camp SP; Working Groups of the American Heart Association Committee on Exercise, Cardiac Rehabilitation, and Prevention; Councils on Clinical Cardiology and Cardiovascular Disease in the Young. Recommendations for physical activity and recreational sports participation for young patients with genetic cardiovascular diseases. Circulation. 2004 Jun 8;109(22):2807-16. Read full article.