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Research in Gastroenterology & Hepatology

The Basic Science Research Program

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The Basic Science Research Program conducts original investigations in scientific fields related to the physiology or pathophysiology of the digestive system, including the gastrointestinal tract, liver and pancreas, and then applies the knowledge gained from research to improve the care of patients with diseases of the digestive system.

The Johns Hopkins Center for Epithelial Disorders

The Johns Hopkins Center for Epithelial Disorders focuses on research into the physiology and pathophysiology of epithelial cells of the gastrointestinal tract, liver, pancreas and kidney. Epithelial cells line the cavities in the body and also cover flat surfaces. These cells have sidedness other than in and outside, facing different surfaces on the apical versus basal surface.

Conte Digestive Diseases Basic and Translational Research Core Center

The focus of the Conte Digestive Diseases Basic and Translational Research Core Center is regulation of epithelial function, especially via changes in signal transduction, trafficking and development.

NIH-supported Training Grants

The Division of Gastroenterology and Hepatology has two ongoing training grants funded by the National Institutes of Health (NIH):

  • Digestive diseases, funded by the National Institute of Diabetes, Digestive and Kidney Diseases (NIDDK)
  • Alcohol research, funded by the National Institute of Alcohol Abuse and Alcoholism (NIAAA)

Ongoing Research

Researchers examine every facet of the digestive system to find better ways to treat illnesses and conditions that originate in the gastrointestinal system, liver and pancreas, from genetic biomarkers and molecular pathogenesis to the role of alcohol consumption and nutrition. Read descriptions of the division’s laboratories and studies.


Clinical Trials

Clinical trials in the Division of Gastroenterology and Hepatology study the physiology or pathophysiology of the digestive system, including the gastrointestinal tract, liver and pancreas. The goal of clinical trials is to improve the care of patients with digestive diseases.


Funding

Initially established with the generous contribution of Harvey and Lyn Meyerhoff, the majority of current research funding in basic science comes from investigator-initiated independent grant support from the NIH. Funding is also provided by major national organizations such as the American Gastroenterology Association, American Liver Foundation, American Heart Association, American Cancer Society, Crohn’s and Colitis Foundation of America and a variety of private sources including major pharmaceutical firms.

 

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