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The Edward D. Miller, MD, Professorship in Anesthesiology Research

Nicholas Flavahan, PhD

Nicholas A. Flavahan, PhD

Dr. Nicholas A. Flavahan, the inaugural Edward D. Miller, MD, Professor of Anesthesiology Research, has had a distinguished biomedical career. He obtained his PhD in cardiovascular physiology and pharmacology in 1983 at the University of Glasgow in Scotland, United Kingdom. He then joined the Mayo Clinic in Rochester, Minnesota, as a Mayo Foundation senior research fellow and was appointed assistant professor of pharmacology at the Mayo Clinic in 1987. Dr. Flavahan stayed at the Mayo Clinic until 1989 when he joined the faculty of Johns Hopkins University as assistant professor of medicine and was promoted to associate professor of medicine in 1991. In 1997, he was recruited to The Ohio State University to help create the Heart and Lung Research Institute where he was deputy director of the institute as well as professor of internal medicine, physiology and cell biology. In September of 2006, Dr. Flavahan returned to The Johns Hopkins University where he was appointed professor, director of research and vice chair of the Department of Anesthesiology and Critical Care Medicine.

Dr. Flavahan is one of the world's top molecular vascular pharmacologists. He has published over 100 peer-reviewed manuscripts and has been funded continuously by the NIH for more than 20 years. Among many firsts, he discovered the molecular mechanisms underlying cold-induced vasoconstriction in the cutaneous circulation and its contribution to normal physiology and vascular disease. Dr. Flavahan has also been an effective teacher and mentor, with many of trainees advancing to leadership positions in the pharmaceutical industry and academic medicine.

Since returning to Johns Hopkins University, Dr. Flavahan has had a dramatic influence on the research activity of the Department of Anesthesiology and Critical Care Medicine, revamping the infrastructure for conducting basic clinical and translational research, redefining mechanisms for scientific interaction, reorganizing and facilitating the grant submission process, and providing structured and transparent mechanisms for young trainees and junior faculty to achieve independence and career advancement.

About The Edward D. Miller, MD, Professorship

Edward D. Miller, MDDr. Edward D. Miller was named chief executive officer of Johns Hopkins Medicine, the 13th dean of the Johns Hopkins University School of Medicine and vice president for medicine of The Johns Hopkins University in January 1997. His appointment followed a year-long national search for the first-ever CEO of Johns Hopkins Medicine, a new organization at that time that formally integrated operations and planning of the School of Medicine with the Johns Hopkins Health System and hospital to ensure their continued preeminence in education, discovery, and patient care. As CEO, Dr. Miller, who retired in 2012, was responsible for both the school and the health system and reported directly to the university president and the chairman of the board of Johns Hopkins Medicine.

Under his aegis, both The Johns Hopkins Hospital and School of Medicine continued to be ranked among the very best in the nation by U.S. News & World Report, and the school continues to rank at the top in NIH research funding. As part of Dr. Miller's vision to improve access to Johns Hopkins Medicine through the development of a regional, integrated health care delivery system, Howard County General Hospital, strategically located between Baltimore and Washington, was acquired and integrated into Johns Hopkins Medicine. In addition, several highly successful suburban outpatient centers were constructed and strategic affiliations were formed with other area hospitals. Dr. Miller also greatly broadened Johns Hopkins Medicine's international presence with the creation of Johns Hopkins Singapore and the forging of affiliations and management relationships with hospitals in the United Arab Emirates, Turkey, Central America, Lebanon, and Japan.

One of his most significant accomplishments as dean/CEO was the massive rebuilding and renovation projects that have transformed the East Baltimore medical campus into a medical center where the most modern of buildings sit among the most historic. The jewel in the crown of this campus revitalization effort has been one of the largest hospital construction projects in the nation – two new state-of-the-art hospitals for adult and pediatric patients. Other important campus construction projects completed under Dr. Miller's tenure include clinical and research buildings for the Sidney Kimmel Comprehensive Cancer Center, the Broadway Research Building, the Anne and Mike Armstrong Medical Education Building and the Robert H. and Clarice Smith building that is part of the Wilmer Eye Institute.

To maintain Johns Hopkins Medicine and the City of Baltimore as key players in the biotechnology industry, Dr. Miller assisted the city and state in its development of the East Baltimore Life Sciences and Technology Park that is already serving as the linchpin for redevelopment of a deteriorating neighborhood near the campus.

Near the top of Dr. Miller's accomplishments was his strengthening of the institution's historic commitment to patient and research volunteer safety. He established the Center for Innovation in Quality Patient Care and implemented a host of related initiatives to improve patient safety, ranging from implementation of an automated computer prescription system that helps prevent errors in ordering medications to a functional unit-based program that pairs senior level JHM executives with health care providers to identify and resolve safety issues. These safety programs have been emulated nationally and internationally.

Dr. Miller also directed the implementation of a diversity initiative that places diversity and inclusion alongside excellence, integrity, and collegiality as core fundamentals within Johns Hopkins Medicine, and under his direction a new School of Medicine curriculum, Genes to Society, was developed and introduced, representing the first wholesale academic overhaul at the school in two decades. The curriculum, nearly six years in the making, centers on advances in understanding of the human genome and will feature new courses and modified existing ones. He also became Johns Hopkins Medicine's chief fundraiser, presiding over a campaign that brought in $2.2 billion, more than any other academic medical institution has attracted in a single campaign.

An anesthesiologist who has authored or co-authored more than 150 scientific papers, abstracts, and book chapters, Dr. Miller joined Johns Hopkins in 1994 as professor and director of the Department of Anesthesiology and Critical Care Medicine and was named interim dean of the School of Medicine in 1996. He came to Hopkins after eight years at Columbia University, where he served as professor and chairman of the Department of Anesthesiology. Prior to that, he spent 11 years at the University of Virginia.

Dr. Miller's research has focused on the cardiovascular effects of anesthetic drugs and vascular smooth muscle relaxation. The recipient of an NIH Career Research Development Award, he has served as president of the Association of University Anesthesiologists, editor of Anesthesia and Analgesia, and editor of Critical Care Medicine. He served on the board of the International Anesthesia Research Society and was chairman of the FDA's Advisory Committee on Anesthesia and Life Support Drugs.

Dr. Miller is a member of the Institute of Medicine of the National Academy of Sciences and is a fellow of the Royal College of Physicians and the Royal College of Anaesthetists. He is also a member of the State of Maryland's Health Care Access and Cost Commission and serves on the boards of Care Fusion and the PNC Bank.

Born in February 1943 in Rochester, New York, Dr. Miller received his AB from Ohio Wesleyan University and his MD from the University of Rochester School of Medicine and Dentistry. He was a surgical intern at University Hospital in Boston, chief resident in anesthesiology at Peter Bent Brigham Hospital in Boston, and a research fellow in physiology at Harvard Medical School. He also spent a sabbatical year as a senior scientist in the Department of Pharmacology and Physiology of Hospital Necker in Paris. He and his wife, Lynne, are the parents of four adult children.

 
 

Grand Rounds
Calendar and Webcasts

Grand Rounds take place Thursdays at 7 AM in Hurd Hall.

10/2: "Integrating Perioperative And Palliative Care Through Patient-Centered Outcomes Research (PCOR)" – Rebecca Aslakson, MD, PhD
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Eighth Robert A. Abraham, MD Endowed Lecture: "Post-Cesarean Pain Management: Past, Present, and Future" – Brendan Carvalho, MBBCh, FRCA, MDCH
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Learn more about Robert A. Abraham, MD >>

"Translational Therapies for Pediatric Traumatic Brain Injury" – Courtney Robertson, MD
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