javascript image slider
 
 

Charles W. Hogue, Jr., MD

Charles W. Hogue, Jr., MD

Professor, Department of Anesthesiology and Critical Care Medicine
Division Chief, Adult Anesthesia
The Johns Hopkins University School of Medicine
Sheikh Zayed Tower
1800 Orleans Street
Baltimore, MD 21287

Phone: 410-614-1516

www.meddium.com/charleshogue

The primary focus of Dr. Hogue’s research is the study of methods to improve outcomes from cardiovascular surgery with a particular focus on brain and kidney injury. In particular, he and his colleagues are investigating methods to monitor cerebral blood flow autoregulation noninvasively and in real time. Normally, blood flow to the brain is kept constant across a range of blood pressures to ensure adequate blood flow that meets the metabolic demands of the brain. This process is termed cerebral autoregulation. When blood pressure is below the limits of autoregulation, blood flow to the brain is directly related to blood pressure: the lower the blood pressure, the lower the blood flow. This condition could predispose patients to stroke, especially those who have cerebral vascular disease. Conversely, when blood pressure is above the upper limit of autoregulation, brain blood flow exceeds metabolic needs. This condition may lead to brain edema and possibly cerebral microembolisms that contribute to brain injury.

Dr. Hogue and collaborators at the University of Cambridge, England, have developed a method to monitor cerebral autoregulation noninvasively by using near-infrared spectroscopy (NIRS). Two, self-adhesive sensors are placed on the patient’s forehead and connected to an oximetry monitor. Clinical and laboratory experiments have shown that processing of the NIRS signals collected provides an acceptable surrogate for monitoring changes in cerebral blood flow. Hogue and his colleagues believe that the this approach can be used to optimize an individual patient’s blood pressure to avoid loss of cerebral autoregulation, particularly during procedures such as cardiopulmonary bypass.

Download CV Adobe PDF

Learn more about Dr. Hogue

Dr. Hogue's Biomedical Research Bio

Learn more about Biomedical Research

 
 

Grand Rounds

Grand Rounds take place Thursdays at 7 AM in Hurd Hall. Windows Media Player is required to view webcasts.

6/4: "Preclinical and Clinical Research on Intracerebral Hemorrhage" – Jian Wang, MD, PHD and Wendy Ziai, MD, MPH
Watch webcast >>

6/5: ACCM Biennial – 8:00am-12:00pm, Zayed 6206

6/11: Thirteenth Donald W. and Marjorie A.M. Benson Lectureship on Pain Medicine – Donna L. Hammond, PhD

6/18: Patient Based Learning Discussion – Tracey Smith Stierer, MD

6/25: Quality Assurance Committee Meeting

7/2: State of the Department – Colleen Koch, MD, MS, MBA, FACC, ACCM Director

7/9: Highlighting Presentation Techniques" – Todd Dorman, MD, FCCM

7/16: Mark C. Rogers Lectureship: Future Trends in Reimbursement of Hospital-Based Physicians – Chet Burrell

"Serving Leadership" – John Porcari, Third River Partners
Watch webcast >>

"ACCM Strategic Plan" – Colleen Koch, MD, MS, MBA, FACC, ACCM Director
Watch webcast >>

Archived webcasts >>

 

Out of State and International Patients

Make a Gift

 

 
 
 
 
 

© The Johns Hopkins University, The Johns Hopkins Hospital, and Johns Hopkins Health System, All rights reserved.

Legal Disclaimer