Nickolas Papadopoulos, Ph.D.

Selected Publications

1. Jiao, Y.; Shi, C.; Edil, B.H.; de Wilde, R.F.; Klimstra, D.S.; Maitra, A.; Schulick, R.D.; Tang, L.H.; Wolfgang, C.L.; Choti, M.A.; Velculescu, V.E.; Diaz, L.A., Jr.; Vogelstein, B.; Kinzler, K.W.; Hruban, R.H.; Papadopoulos, N. DAXX/ATRX, MEN1, and mTOR Pathway Genes Are Frequently Altered in Pancreatic Neuroendocrine Tumors. Science. 2011 Jan 20;In Press.
2. Parsons, D.W.; Li, M.; Zhang, X.; Jones, S.; Leary, R.J.; Lin, J.C.; Boca, S.M.; Carter, H.; Samayoa, J.; Bettegowda, C.; Gallia, G.L.; Jallo, G.I.; Binder, Z.A.; Nikolsky, Y.; Hartigan, J.; Smith, D.R.; Gerhard, D.S.; Fults, D.W.; Vandenberg, S.; Berger, M.S.; Marie, S.K.; Shinjo, S.M.; Clara, C.; Phillips, P.C.; Minturn, J.E.; Biegel, J.A.; Judkins, A.R.; Resnick, A.C.; Storm, P.B.; Curran, T.; He, Y.; Rasheed, B.A.; Friedman, H.S.; Keir, S.T.; McLendon, R.; Northcott, P.A.; Taylor, M.D.; Burger, P.C.; Riggins, G.J.; Karchin, R.; Parmigiani, G.; Bigner, D.D.; Yan, H.; Papadopoulos, N.; Vogelstein, B.; Kinzler, K.W.; Velculescu, V.E. The Genetic Landscape of the Childhood Cancer Medulloblastoma. Science. 2010 Dec 16.
3. Jones, S.; Wang, T.L.; Shih Ie, M.; Mao, T.L.; Nakayama, K.; Roden, R.; Glas, R.; Slamon, D.; Diaz, L.A., Jr.; Vogelstein, B.; Kinzler, K.W.; Velculescu, V.E.; Papadopoulos, N. Frequent mutations of chromatin remodeling gene ARID1A in ovarian clear cell carcinoma. Science. 2010 Oct 8;330(6001):228-231.
4. He, Y.; Wu, J.; Dressman, D.C.; Iacobuzio-Donahue, C.; Markowitz, S.D.; Velculescu, V.E.; Diaz, L.A., Jr.; Kinzler, K.W.; Vogelstein, B.; Papadopoulos, N. Heteroplasmic mitochondrial DNA mutations in normal and tumour cells. Nature. 2010 Mar 25;464(7288):610-614.
5. Ericson, K.; Gan, C.; Cheong, I.; Rago, C.; Samuels, Y.; Velculescu, V.E.; Kinzler, K.W.; Huso, D.L.; Vogelstein, B.; Papadopoulos, N. Genetic inactivation of AKT1, AKT2, and PDPK1 in human colorectal cancer cells clarifies their roles in tumor growth regulation. Proc Natl Acad Sci U S A. 2010 Feb 9;107(6):2598-2603.