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Karthik S Suresh, M.D.

Photo of Dr. Karthik S Suresh, M.D.

Assistant Professor of Medicine


Languages: English, Tamil

Expertise: General Internal Medicine

Research Interests: ROS signaling; endothelial cell biology; vascular biology; calcium singaling


Johns Hopkins Bayview Medical Center

4940 Eastern Avenue
301 Building, 1st Floor
Baltimore, MD 21224 map
Phone: 410-955-9441


Dr. Karthik Suresh is an assistant professor of medicine at the Johns Hopkins University School of Medicine. His areas of clinical interest and expertise include general internal medicine, pulmonology and critical care medicine.

He earned his B.S. and M.D. from the University of Louisville School of Medicine. He completed his residency at the Osler Medicine training program at Johns Hopkins, and performed a fellowship in Pulmonary / Critical Care Medicine at Johns Hopkins. more


  • Assistant Professor of Medicine

Departments / Divisions



  • MD, University of Louisville School of Medicine (2008)


  • Johns Hopkins University School of Medicine / Internal Medicine (2011)


  • Johns Hopkins University School of Medicine / Pulmonary Medicine (2012)
  • Johns Hopkins University School of Medicine (2016)

Board Certifications

  • American Board of Internal Medicine / Internal Medicine (2011)
  • American Board of Internal Medicine / Pulmonary Disease (2015)

Research & Publications


Our lab focuses on the mechanisms of microvascular endothelial dysfunction across two lung diseases with high morbidity and mortality: Acute Lung Injury (ALI) and Pulmonary Arterial Hypertension (PAH). Using endothelial cells (ECs) isolated from humans, mice and rats, as well as animal models of ALI and PAH, we investigate the role of elevated reactive oxygen species (ROS) and intracellular calcium in regulating disease-specific abnormalities in EC function. In ALI, we study signaling pathways governing formation of paracellular gaps between endothelial cells, which clinically leads to alveolar flooding and hypoxemia. For PAH, we study the effect of ROS and calcium signaling on EC migration and proliferation as it relates to formation of vaso-occlusive lesions in the distal arterioles of the lung, a known contributor to elevations in pulmonary artery pressures in this disease.

Selected Publications

Huetsch J, Suresh K, Bernier M, Shimoda LA. Update on Novel Targets and Potential Treatment Avenues in Pulmonary Hypertension. Am J Physiol Lung Cell Mol Physiol 2016 [Epub ahead of print]

Suresh K, Servinsky LE, Reyes J, Baksh S, Undem C, Caterina MJ, Pearse DB, Shimoda LA. Hydrogen Peroxide-induced Calcium Influx in lung microvascular endothelial cells involves TRPV4. Am J Physiol Lung Cell Mol Physiol. 309: L1467–L1477, 2015

Suresh K, Belchis D, Askin F, Pearse DB, Terry, P. "Occupational asthma due to aerosolized lipophilic coating materials", Lung 194(5): 787-9, 2016.

Suresh K, Shimoda LA. Lung Circulation, Compr Physiol 6:897-943, 2016

Suresh K, Servinsky LE, Reyes J, Undem C, Zaldumbide J, Rentsendorj O, Modekurty S, Dodd-o J, Pearse DB, Shimoda LA.CD36 mediates H2O2-induced calcium influx in lung microvascular endothelial cells Am J Physiol Lung Cell Mol Physiol. 312: L143-153, 2016

Patient Ratings & Comments

The Patient Rating score is an average of all responses to physician related questions on the national CG-CAHPS Medical Practice patient experience survey through Press Ganey. Responses are measured on a scale of 1 to 5, with 5 being the best score. Comments are also gathered from our CG-CAHPS Medical Practice Survey through Press Ganey and displayed in their entirety. Patients are de-identified for confidentiality and patient privacy.

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