Why do some people become obese while others remain lean? We propose that individuals differ in appetite-related characteristics that manifest early in life, show genetic influence, and interact with environmental factors (e.g. family feeding practices) to predict eating behavior and weight.
To understand more about the character and origins of these characteristics (e.g. food cue responsiveness, satiety sensitivity), my lab uses a range of methods including behavioral tests, self- and parent-report questionnaires, genotyping, hormonal assays, and neuroimaging techniques (fMRI, MRI, PET).
Ongoing research projects include investigations of appetite and body weight in infants, children, adolescents and adults, including studies of eating behavior in anorexia nervosa, attention-deficit hyperactivity disorder, cystic fibrosis, and individuals undergoing bariatric surgery.
We are conducting a research study in children (4-13 y old) and their biological mothers. The study involves two visits for 3-4 hours each, and includes fMRI scan (child only), body composition measurements (height, weight, waist), questionnaires, computer tasks, buffet meals, and saliva collection. Compensation is up to $125, plus $10 travel costs for each visit. If interested, please call 410-955-5099 or email Appetite@jhu.edu.
Carnell S, Grillot C, Ungredda T, Ellis S, Mehta N, J Holst & Geliebter A (2017) Morning and afternoon appetite and appetite hormone responses to meal and stress challenges in obese individuals with and without Binge Eating Disorder. International Journal of Obesity. Epub ahead of print 2017 Dec 13. PMID: 29235554
Carnell S, Benson L, Chang K, Wang Z, Huo Y, Geliebter A & Peterson BS (2017) Neural correlates of familial obesity risk and overweight in adolescence. Neuroimage, 159, 236-247. PMID: 28754348
Dinkevich E, Leid L, Pryor K, Wei Y, Huberman H & Carnell S (2015) Mothers' feeding behaviors in infancy: do they predict child weight trajectories? Obesity, 23(12):2470-2476. Epub Nov 5. PMID: 26537027
Carnell S, Haworth CMA, Plomin R & Wardle J (2008) Genetic influence on appetite in children. International Journal of Obesity, 32, 1468-1473. PMID: 18679413
Carnell S & Wardle J (2007) Measuring behavioural susceptibility to obesity: validation of the Child Eating Behaviour Questionnaire. Appetite, 48, 104-113. PMID: 16962207