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Georg Oeltzschner, Ph.D.

Photo of Dr. Georg Oeltzschner, Ph.D.
  • Instructor of Radiology and Radiological Science

Research Interests

In vivo magnetic resonance spectroscopy (MRS)

Background

Dr. Georg Oeltzschner is an Instructor in the Johns Hopkins Medicine Department of Radiology and Radiological Science. His research interests concern the development of advanced magnetic resonance spectroscopy (MRS) acquisition techniques for low-concentration brain metabolites and novel data processing and quantification methods. He is involved in a number of national and international projects using these techniques to study the neurochemistry in the healthy and diseased human brain.

Before completing a postdoctoral fellowship under the auspices of Dr. Richard Edden at Johns Hopkins, Dr. Oeltzschner received his undergraduate degree in Physics and graduate degree in Natural Sciences from Heinrich Heine University in Düsseldorf, Germany.

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Titles

  • Instructor of Radiology and Radiological Science

Departments / Divisions

Education

Degrees

  • Ph.D., Heinrich-Heine University - Dusseldorf (Germany) (2015)

Research & Publications

Research Summary

Dr. Oeltzschner's research is dedicated to developing modern techniques to measure levels of important biochemicals in the living human brain using magnetic resonance spectroscopy. He is particularly focused on improving the detection of neurotransmitters (GABA, glutamate, aspartate), antioxidants (glutathione, ascorbate), and potential molecular markers of brain tumor mutations (2-hydroxyglutarate, cystathionine).

The techniques he develops are used to investigate the neurochemical confounds in a wide range of neurological and psychiatric disorders. Currently, he studies the levels of brain metabolites in patients with mild cognitive impairment. Further research projects he is involved in concern various neurodevelopmental disorders (autism spectrum disorder, attention-deficit/hyperactivity disorder, Tourette’s syndrome), tuberous sclerosis, hepatic encephalopathy, and glioma.

A recent major focus of his attention is the standardization of data acquisition and analysis. He believes that the magnetic resonance community can reap great benefit from embracing the practices of the Open Science movement: adapting code sharing, standardizing data acquisition, and streamlining pipelines for processing, quantifying, and interpreting spectroscopic data.

Lab Website: Georg Oeltzschner

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