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Evan Martin Bloch, M.B.Ch.B., M.D., M.S.
Associate Professor of Pathology
Languages: English, Afrikaans, Spanish
Research Interests: Neglected Infectious diseases; transfusion transmitted infectious; Babesia; Zika
Dr. Bloch is originally from South Africa where he completed his medical school (University of Cape Town) and clinical training, which first spurred an interest in infectious disease. Following completion of a combined residency in Anatomic and Clinical Pathology (Tufts Medical Center), post-graduate fellowship in Transfusion Medicine (University of California San Francisco [UCSF]) and Masters in Global Health (UCSF) he continued research at Blood Systems Research Institute, while continuing to teach at UCSF in Laboratory Medicine and Global Health Sciences. He joined the faculty at Johns Hopkins University in the Department of Pathology in 2015.
Dr. Bloch's major research focus is in neglected (e.g. Babesia) and emerging infectious diseases (e.g. Zika, Oropouche, Mayaro viruses), particularly in the context of blood transfusion safety. As one example, He has a longstanding interest in babesiosis, a tick-borne parasitic infection that is endemic to parts of the United States. Although infection is characterized by mild illness in immune competent adults, Babesia poses significant risk to those patients at extremes of age, the immunocompromised and the asplenic. These high-risk groups are notably overrepresented among the transfused population accounting for complicated disease and even death in transfusion-transmitted babesiosis (TTB). Babesia is globally ubiquitous, yet lack of awareness, in part due to historically limited diagnostic tools, has impeded greater recognition of its role in human disease. Dr. Bloch has participated in studies to develop both antibody and molecular tests for detection of Babesia. The studies have also been used to understand the biology of Babesia infection as well as to conduct surveillance outside of the US.
Dr. Bloch’s research has been funded through the National Heart, Lung and Blood Institute of the National Institutes of Health (NIH) through SBIR and R21 grant mechanisms. Ongoing projects are funded through International Society of Blood Transfusion, the Bill and Melinda Gates Foundation, NIAID and the Fisher Center Discovery Program.
The author of 49 peer-reviewed publications, Dr. Bloch is a member of the International Society of Blood Transfusion infectious disease working party (co-chair parasite sub-group) and AABB (formerly American Association of Blood Banks). He has consulted on transfusion policy and development of clinical transfusion guidelines, and hopes to use blood transfusion as a platform for infectious disease surveillance so as to guide programmatic support, particularly in low-resource settings.
- Associate Professor of Pathology
- MBChB, University of Cape Town Medical School (1999)
- Tufts-New England Medical Center Hospitals / Anatomic and Clinical Pathology (2008)
- University of California San Francisco School of Medicine (2009)
- American Board of Pathology / Clinical Pathology (2009)
Research & Publications
- Epidemiology and intervention trials focused on neglected (e.g. Babesia) and emerging (eg. Zika, Oropouche, Mayaro) infectious disease, specifically in the context of blood transfusion safety
- Clinical and operational blood safety in low resource settings
Bloch EM, Ness PM, Tobian AAR, Sugarman J. Revisiting Blood Safety Practices Given Emerging Data about Zika Virus. N Engl J Med 2018;378: 1837-41
Bloch EM, Mabula K, Levin A, Mrango Z, Weaver J, Munoz B and West SK. Babesia microti and Malaria infection in Africa: a pilot serosurvey in Kilosa district, Tanzania. American Journal of Tropical Medicine and Hygiene April 2018
T Brooks T, Roy-Burman A, Tuholske C, Busch MP, Bakkour S, Stone M, Linnen JM, Gao K, Coleman J, and Bloch EM. Evolution of Zika virus outbreak on Roatán, Honduras: A real-time observation of the epidemic. Emerg Infect Dis 2017;23
Bloch EM, Lee TH, Krause PJ, Telford SR 3rd, Montalvo L, Chafets D, Usmani-Brown S, Lepore TJ, Busch MP. Development of a real-time polymerase chain reaction assay for sensitive detection and quantitation of Babesia microti infection. Transfusion 2013;53: 2299-306
Bloch EM, Simon, MS and Shaz, BH. Emerging Infections and Blood Safety in the 21st Century. Ann Intern Med Mar 15 2016
Activities & Honors
- AABB (Formerly American Association of Blood Banks)
- ISBT (International Association of Blood Transfusion)