Dr. Vandrey's research focuses primarily on the behavioral pharmacology of cannabis (marijuana) and includes controlled laboratory studies with adult research volunteers, clinical trials, web-based survey research, and natural history studies with patient populations using cannabis/cannabinoids for therapeutic purposes. He has also been engaged in research on nicotine and tobacco regulatory science and treatment. He has published over 60 peer reviewed journal articles and 10 book chapters. Dr. Vandrey aspires to conduct objective research that addresses critical questions related to regulation and policy. His work helped characterize the cannabis withdrawal syndrome, has provided novel data about the comparative pharmacokinetics and corresponding pharmacodynamics of cannabinoids across routes of administration, explored medications that are potential adjuncts to behavior therapy in the treatment of cannabis use disorder, examined the effects of cannabis on sleep, and evaluated both the risks and benefits of medicinal use of cannabis/cannabinoids for various health conditions.