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Mark Wu, M.D., Ph.D.

Mark Nan Wu, M.D., Ph.D.

Photo of Dr. Mark Wu, M.D., Ph.D.

Associate Professor of Neurology


Expertise: Narcolepsy, Neurology, Sleep, Sleep Disorders, Sleep Medicine

Research Interests: Genetic mechanisms underlying regulation of sleep and neuronal excitability, using simple model organisms; Investigating the genetic basis of Familial Sleep Paralysis more

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The Johns Hopkins Hospital (Main Entrance)
Appointment Phone: 443-287-3313

1800 Orleans St.
Sheikh Zayed Tower
Baltimore, MD 21287 map
Phone: 410-550-5864

Johns Hopkins Outpatient Center
Appointment Phone: 410-955-9441

601 N. Caroline St.
Baltimore, MD 21287 map
Phone: 410-550-5864

Johns Hopkins Bayview Medical Center
Appointment Phone: 410-550-5624

4940 Eastern Avenue
Baltimore, MD 21224 map


Dr. Mark Wu specializes in sleep disorders and has a particular interest in narcolepsy, idiopathic hypersomnolence, and sleep paralysis.

Dr. Mark Wu received his M.D. and Ph.D. degrees from Baylor College of Medicine in Houston, Texas. After completing his internship at Baylor, he went to UCLA for residency training in Neurology. He then completed a Sleep Medicine fellowship at the University of Pennsylvania. more


  • Associate Professor of Neurology
  • Associate Professor of Medicine
  • Associate Professor of Neuroscience

Centers & Institutes



  • MD PhD, Baylor College of Medicine (2001)


  • David Geffen School of Medicine at UCLA - GME / Neurology (2005)


  • Pennsylvania Hospital / Sleep Medicine (2007)

Board Certifications

  • American Board of Psychiatry And Neurology / Neurology (2006)
  • American Board of Psychiatry and Neurology / Sleep Medicine (2007)

Research & Publications


The Wu Lab studies the molecular, genetic, and cellular mechanisms underlying sleep in Drosophila.

Activities & Honors


  • Discovery Innovation Award, The Johns Hopkins University School of Medicine, 2017

Videos & Media

Recent News Articles and Media Coverage

Gene Mutation Could Play Role In Sleep Problems, Fly Study Shows, HuffingtonPost (03/14/2014)

The Gene That Causes Sleep, WYPR-FM (03/14/2014)

Sleep During the Day May Throw Genes Into Disarray, US News (01/21/2014)

Patient Ratings & Comments

The Patient Rating score is an average of all responses to physician related questions on the national CG-CAHPS Medical Practice patient experience survey through Press Ganey. Responses are measured on a scale of 1 to 5, with 5 being the best score. Comments are also gathered from our CG-CAHPS Medical Practice Survey through Press Ganey and displayed in their entirety. Patients are de-identified for confidentiality and patient privacy.

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