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Rafael H Llinas, M.D.
Director, Neurology at Johns Hopkins Bayview
Professor of Neurology
Expertise: Cerebrovascular Diseases, Neurology, Stroke
Research Interests: Atherosclerotic disease, Thrombolysis and stroke. Intracerebral hemorrhage
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Dr. Rafael Llinas serves as the Director of Neurology at the Johns Hopkins Bayview Medical Center. His clinical interests include acute stroke treatments, neurovascular imaging and migraine as related to cerebrovascular disease. He also serves as the associate director of the neurology residency program. He was instrumental in establishing the Johns Hopkins Bayview Medical Center Stroke Center. In 2005, in recognition of the Stroke Centers organizational efforts in stroke care, the institution was granted certification as a Primary Stroke Center by the Joint Commission on Accreditation of Healthcare Organizations.
Dr. Llinas primary areas of research interests include diffusion-perfusion imaging of stroke, intravenous and intra-arterial thrombolysis for stroke, education of physicians and nurses in stroke identification and stroke care, stroke units and stroke centers.
Dr. Rafael Llinas received his medical degree from the New York University School of Medicine. He completed a medical internship at the Boston City Hospital and was a neurology resident in the Harvard-Longwood neurology training program. Following his residency, he was a stroke and cerebrovascular disease fellow for two years at Beth Israel Hospital, Harvard University.
- Director, Neurology at Johns Hopkins Bayview
- Director, Johns Hopkins Neurology Residency Program
- Professor of Neurology
Departments / Divisions
- Neurology - Neurology-Vascular
Centers & Institutes
- MD, New York University School of Medicine (1994)
- Brigham and Womens Hospital / Neurology (1998)
- Beth Israel Deaconess Medical Center (2000)
- American Board of Psychiatry and Neurology / Neurology-General (1999)
Research & Publications
Selected PublicationsView all on Pubmed
Linfante, I; Llinas, RH; Caplan, LR; and Warach,S. (1999). MRI features of intracerebral hemorrhage within 2 hours from symptom onset. Stroke; 30:2263-2267.
Llinas, RH and Henderson, G. (1999). Tremor presenting as Pseudoventricular Tachycardia. New England Journal of Medicine Vol 341 No 17 page 1275.
Murray, BJ; MD, Llinas, RH; Caplan, LR; Scammell, T; and Pascual-Leone, A. (2000) Cerebral Venous Thrombosis Presenting as Acute Migrographia and Hypophonia. Neurology 54(3):751-753.
Saposnik, G ; Caplan, LR; Gonzalez, L; Baird, AE; Dashe, J; Luraschi1,A ; Llinas, RH; Lepera, S ; Linfante, L; Chaves, C; Kanis, K; Sica1, RE; and Rey, RC. (2000). Differences in Stroke Subtypes among Natives and Caucasians in Boston and Buenos Aires. Stroke; 31:2385-2389.
Linfante, I; Llinas, RH; and Schlaug, G; Chaves, C; Warach, S; Caplan, LR (2001) Diffusion-Weighted Imaging and National Institutes of Health Stroke Scale in the Acute Phase of Posterior-Circulation Stroke. Arch Neurol; 58:621-628.
Anschel DJ, Simon DK, Llinas RH, Joseph JT. (2002) Spongiform encephalopathy mimicking corticobasal degeneration. Mov Disord May; 17(3):606-7.
Jaillard A, Hommel M, Baird AE, Linfante I, Llinas RH, Caplan LR, Edelman RR, Warach S. (2002)
Significance of early CT signs in acute stroke. A CT scan-diffusion MRI study. Cerebrovasc Dis; 13(1):47-56.
Linfante I, Llinas RH, Selim M, Chaves C, Kumar S, Parker RA, Caplan LR, Schlaug G. (2002) Clinical
and vascular outcome in internal carotid artery versus middle cerebral artery occlusions after intravenous tissue plasminogen activator. Stroke; 33(8):2066-71.
Restrepo, L; Pradilla, G; Llinas, RH, and Beauchamp, NJ (2003). Perfusion- and Diffusion-Weighted MR ImagingGuided Therapy of Vertebral Artery Dissection: Intraarterial Thrombolysis through an Occipital Vertebral Anastomosis AJNR 24: 1823-1826.
Chaves CJ, Staroselskaya I, Linfante I, Llinas R, Caplan LR, Warach S. (2003). Patterns of perfusion
-weighted imaging in patients with carotid artery occlusive disease. Arch Neurol, 60(2):237-42.
Gottesman, R; Alt, J; Wityk, RJ and Llinas, RH. (2006) Predicting abnormal coagulation in Ischemic Stroke: A potential use in reducing rt-PA delays. Neurology 67:1665-1667.
Hillis AE, Kleinman, JT, Newhart M, Heidler-Gary J, Gottesman R, Barker PB, Aldrich E,
Llinas RH, Wityk R, and Chaudhry P. (2006) Restoring Cerebral Blood Flow Reveals Neural Regions
Critical for Naming J. Neurosci. 26: 8069-8073.
Blakeley JO, Llinas RH. Thrombolytic therapy for acute ischemic stroke. J Neurol Sci. 2007 Oct 15;261(1-2):55-62. Epub 2007 Jul 5.20.
Levy M, Turtzo C, Llinas RH. Superficial siderosis: a case report and review of the literature. Nat Clin Pract Neurol. 2007 Jan;3(1):54-8; quiz 59.
Hillis AE, Gold L., Kannan V., Cloutman L., Kleinman JT., Newhart M., Heidler-Gary J., Davis C., Aldrich E., Llinas R., and Gottesman RF. (2008) Site of the ischemic penumbra as a predictor of potential for recovery of functions. Neurology 2008; 71:184-189.
Turtzo LC., Kleinman, J, and Llinas, RH. Capgras syndrome and unilateral special neglect in non-convulsive status epilepticus Behavioural Neurology Nov 19 (2008) 1-4. 23.
Llinas RH. Ischemic stroke and ICU care. Semin Neurol. 2008 Nov; 28 (5):645-56. Epub 2008 Dec 29.
Cronin CA., Weisman CJ., Llinas RH. Stroke treatment: beyond the three-hour window and in the pregnant patient. Ann N Y Acad Sci. 2008 Oct; 1142:159-78.
Turtzo, LC, Gottesman R, Llinas RH Diffusion weighted imaging showing "pearls" predict large vessel disease as stroke etiology. Cerebrovascular Disease 2009 In press.
Ostrow L, Llinas RH. The Eastchester Clapping Sign (ECS): A Novel Test of Parietal Neglect.
Annals of Neurology 2009- In press.
Activities & Honors
- Frank R. Ford Award for Outstanding Teacher in Neurology award, Johns Hopkins Department of Neurology, 2002
- National Teacher Recognition Award, American Academy of Neurology, 2004
- Nominated and Elected Fellow, The American Heart Association (FAHA), 2004
- Service Excellence Annual Award, Johns Hopkins School of Medicine, 2005
- Service Excellence in Teaching Award, Johns Hopkins Osler, 2005
- Frank R. Ford Award for Outstanding Teacher in Neurology award, Johns Hopkins Department of Neurology, 2005
- Fellow, American Neurological Association (FANA), 2006
- Member, Miller-Coulson Academy of Clinical Excellence
- Order of the Meritorious Citizen, Alcaldia Bucaramanga, Columbia
- American Academy of Neurology
- American Heart Association
- American Neurological Association
- American Stroke Association
- Royal Society of Medicine (UK)