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Una D McCann, M.D.

Photo of Dr. Una D McCann, M.D.
  • Associate Program Director JHBMC GCRC
  • Professor of Psychiatry and Behavioral Sciences
Female

Languages: English, Spanish

Expertise

Adult Psychiatry, Anxiety Disorders, Obsessive-Compulsive Disorders, Post Traumatic Stress, Psychiatry, Psychiatry and Behavioral Sciences

Research Interests

Amphetamine-induced Monoamine Neurotoxicity; Neurobiology of Anxiety Disorders

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Insurance Information

Maryland

410-550-1933

Outside of Maryland

410-464-6641
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International Patients

+1-410-502-7683
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Locations

Johns Hopkins Bayview Medical Center

Appointment Phone: 410-550-1933
5500 Lombard Street
Baltimore, MD 21224 map

The Johns Hopkins Hospital (Main Entrance)

Appointment Phone: 410-955-5104
1800 Orleans St.
Sheikh Zayed Tower
Baltimore, MD 21287 map

Background

Dr. Una McCann is a psychiatric specialist in Baltimore, caring for patients with anxiety disorders, obsessive-compulsive disorders and post-traumatic stress. Dr. McCann serves as Associate Program Director at the Johns Hopkins Bayview Medical Center Graduate Clinical Research Center. She is also Director of the Anxiety Disorders Program and Co-Director of the Center for Interdisciplinary Sleep Medicine and Research at Johns Hopkins School of Medicine.

Dr. McCann received her undergraduate degree in psychology from Princeton University. She earned her M.D. from Duke University School of Medicine. She completed her residency at Stanford University School of Medicine, where she also performed a fellowship in psychiatry. Dr. McCann joined the Johns Hopkins faculty in 1999.

Her research interests include amphetamine-induced monoamine neurotoxicity and the neurobiology of anxiety disorders.

Dr. McCann is a member of the Society for Neuroscience. She speaks both English and Spanish.

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Titles

  • Associate Program Director JHBMC GCRC
  • Director, Anxiety Disorders Program
  • Professor of Psychiatry and Behavioral Sciences
  • Professor of Neurology

Departments / Divisions

Centers & Institutes

Education

Degrees

  • MD, Duke University School of Medicine (1984)

Residencies

  • Stanford University School of Medicine / Psychiatry (1988)

Fellowships

  • Stanford University School of Medicine / Psychiatry (1988)

Board Certifications

  • American Board of Psychiatry And Neurology / Psychiatry (1990)

Research & Publications

Research Summary

Dr. McCann’s two active areas of research are in amphetamine-induced monoamine neurotoxicity (i.e., MDMA, methamphetamine, ephedrine or amphetamine-induced monoaminergic neurotoxicity) and the neurobiology of anxiety disorders. Methods used in both research spheres include neuropharmacology, PET, MRI, fMRI, polysomnography, pharmacological challenge and neuropsychiatric assessment. Studies of amphetamine neurotoxicity also include preclinical studies using microarrays, cell culture, rodents and primates.

Core Facility: Interdisciplinary Sleep, Research and Education (CISRE), Center for

Selected Publications

Williams MS, Ziegelstein RC, McCann UD, Gould NF, Ashvetiya T, Vaidya D. "Platelet Serotonin Signaling in Patients With Cardiovascular Disease and Comorbid Depression." Psychosom Med. 2019 May;81(4):352-362

Garg A, Kapoor S, Goel M, Chopra S, Chopra M, Kapoor A, McCann UD, Behera C. "Functional Magnetic Resonance Imaging in Abstinent MDMA Users: A Review." Curr Drug Abuse Rev. 2015;8(1):15-25

Mueller M, Yuan J, McCann UD, Hatzidimitriou G, Ricaurte GA. "Single oral doses of (±) 3,4-methylenedioxymethamphetamine ('Ecstasy') produce lasting serotonergic deficits in non-human primates: relationship to plasma drug and metabolite concentrations." Int J Neuropsychopharmacol. 2013 May;16(4):791-801

Mueller M, Maldonado-Adrian C, Yuan J, McCann UD, Ricaurte GA. "Studies of (±) 3,4-methylenedioxymethamphetamine (MDMA) metabolism and disposition in rats and mice: relationship to neuroprotection and neurotoxicity profile." J Pharmacol Exp Ther. 2013 Feb;344(2):479-88

Rao V, Mielke M, Xu X, Smith GS, McCann UD, Bergey A, Doshi V, Pham DL, Yousem D, Mori S. "Diffusion tensor imaging atlas-based analyses in major depression after mild traumatic brain injury." J Neuropsychiatry Clin Neurosci. 2012 Summer;24(3):309-15

Academic Affiliations & Courses

Courses and Syllabi

  • Cognitive Behavior Therapy Training (Psychiatry PGY-III)
    2004
  • Anxiety Disorders Seminar
    2004
  • Psychiatry PGY-III Lecture Series
    2004
  • Medical Students Psychiatry Rotation
    2004
  • GIM Psychiatry Lecture Series
    2002
  • Introduction to Clinical Research Practicum
    2002 - 2003
  • Introduction to Clinical Research Course
    2001 - 2003

Activities & Honors

Honors

  • U.S. Army Commissioned Officers Award, 1995
  • Moos Fellowship for Clinical Research in Psychiatry, Stanford University, 1987 - 1988
  • Sigma Xi Award in Psychology, 1980
  • Howard Hughes Foundation Student Scholar, Peter Bent Brigham Hospital, 1980
  • Phi Beta Kappa and Sigma Xi Societies, 1980

Memberships

  • Society for Neuroscience, 1988

Professional Activities

  • Editorial board member, Journal of Women’s Health and Gender Based Medicine
  • Editorial board member, Women in Medicine
  • Editorial board member, Addiciones
  • Editorial board member, Journal of Addiction
  • Editorial board member, Journal of Sleep Disorders: Treatment and Care
  • Editorial board member, WebmedCentral Plus
  • Editorial board member, Psychotherapy and Psychological Disorders

Videos & Media

Recent News Articles and Media Coverage

Hopkins Brain Wise Newsletter articles about Dr. McCann's work:

Translations: Model of a Muddle

Look What They’ve Done to Their Brains

Patient Ratings & Comments

The Patient Rating score is an average of all responses to physician related questions on the national CG-CAHPS Medical Practice patient experience survey through Press Ganey. Responses are measured on a scale of 1 to 5, with 5 being the best score. Comments are also gathered from our CG-CAHPS Medical Practice Survey through Press Ganey and displayed in their entirety. Patients are de-identified for confidentiality and patient privacy.

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