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Deborah Persaud, M.D.

Photo of Dr. Deborah Persaud, M.D.
  • Professor of Pediatrics
Female

Expertise

Pediatric Infectious Disease

Research Interests

Mother-to-child HIV transmission; HIV latency, HIV pathogenesis and cure therapeutics for infants, children and adolescents; SARS-CoV-2 pathogenesis in children ...read more

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Insurance Information

Maryland

410-614-3917

Outside of Maryland

410-464-6641
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International Patients

+1-410-502-7683
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Locations

Johns Hopkins Pediatrics

Appointment Phone: 410-614-3917
200 N. Wolfe Street
Rubenstein Child Health Building
Baltimore, MD 21287 map
Phone: 443-287-3733

Background

Dr. Deborah Persaud is a professor of pediatrics at the Johns Hopkins University School of Medicine. She holds joint appointments in international health and molecular microbiology and immunology at the Johns Hopkins Bloomberg School of Public Health.

A clinician and researcher specializing in the study and treatment of HIV-1 infection in children, she directs the pediatric infectious diseases fellowship program at the Johns Hopkins Children’s Center.

Dr. Persaud received her B.S. in chemistry from York College in New York. A 1985 graduate of the New York University School of Medicine, she trained in pediatrics at Babies Hospital/Columbia Presbyterian Medical Center in New York, where she was chief resident. She was an infectious disease fellow, an Aaron Diamond postdoctoral research fellow and a faculty member at New York University. She joined the Johns Hopkins faculty in 1997, following a visiting lectureship at the Moi University in Eldoret, Kenya.

Her research interests include HIV/AIDS drug development and mother-to-child HIV transmission.

Dr. Persaud is the scientific chair of the HIV CURE Scientific Committee of the International Maternal, Pediatric Adolescent AIDS Clinical Trials (IMPAACT) group. She was awarded the prestigious Elizabeth Glaser Scientist Award for her HIV research and was recognized by Nature magazine in 2013 as one of “Ten People Who Mattered This Year.” She was recognized by Time magazine as among the “100 Most Influential People of 2013” for her pediatric HIV treatment research.

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Titles

  • Professor of Pediatrics

Departments / Divisions

Centers & Institutes

Education

Degrees

  • MD; Medicine, New York University School of Medicine (1985)

Residencies

  • New York-Presbyterian/Columbia University Irving Medical Center / Pediatrics (1989)

Fellowships

  • New York University Medical Center / Pediatric Infectious Diseases (1992)
  • New York University Medical Center (1995)

Board Certifications

  • American Board of Pediatrics / Pediatric Infectious Diseases (1994)

Research & Publications

Research Summary

Dr. Persaud’s research focuses on the immunopathogenesis of HIV latency in perinatal infections in infants, children, and adolescents towards improving HIV therapeutics for this population with the goal of eventual HIV remission and cure. She oversees the development of the clinical trials pipeline for HIV cure therapeutics for the NIH-sponsored International Maternal Pediatric Adolescent AIDS Clinical Trials (IMPAACT) Network. Her laboratory is also a sub-specialty laboratory for NIH-sponsored HIV prevention and cure clinical trials targeting perinatal and adult HIV infections.

Selected Publications

Persaud D, Gay H, Ziemniak C, Chen YH, Piatak M Jr, Chun TW, Strain M, Richman D, Luzuriaga K. Absence of Detectable Viremia after Treatment Cessation in an Infant. NEJM. 2013;7;369 (19):1828-35. PMID:24152233;PMCID PMC 3954754; NIHMS542777

Uprety, P., Patel, K., Karalius, B., Ziemniak, C., Hui, Y.C., Brummel, S.S., Siminski, S., Van Dyke, R.B., Seage III, G.R., Persaud, D. HIV-1 DNA Decay Dynamics with Early, Long-term Virologic Control of Perinatal Infection. CID, 2017; 64 911); 1471-1478. PMID 28329153

Brumme ZL, Sudderuddin H, Ziemniak C, Luzuriaga K, Jones BR, Joy JB, Cunningham CK, Greenough T, Persaud D. Genetic complexity in the replication-competent latent HIV reservoir increases with untreated infection duration in infected youth. AIDS. 2019 Feb 1;33(2):211-218. PMID:30325763

Dhummakupt A, Rubens JH, Anderson T, Powell L, Nonyane BA, Siems LV, Collinson-Streng A, Nilles T, Jones RB, Tepper V, Agwu A, Persaud D. Differences in inducibility of the latent HIV reservoir in perinatal and adult infection. JCI Insight. 2020 Feb 27;5(4). PMID: 31999647

Activities & Honors

Honors

  • Doris Duke Clinician Scientist Award, 1999
  • Elizabeth Glaser Scientist Award, 2005
  • 100 Most Influential People, Time, 2013
  • Ten People Who Mattered This Year, Nature, 2013

Memberships

  • Infectious Diseases Society of America
  • Pediatric Infectious Diseases Society
  • International AIDS Society

Professional Activities

  • Chair, HIV Cure Scientific Committee for the International Maternal, Pediatric Adolescent AIDS Clinical Trials (IMPAACT) Network
  • Committee Member, Immunology, Virology and Vaccine Subcommittee for the Pediatric AIDS Clinical Trials Group, 2001
  • Co-Chair, International AIDS Society Industry Collaborative Group, 2020

Videos & Media

Recent News Articles and Media Coverage

Early Treatment Is Found to Clear H.I.V. in a 2nd Baby, The New York Times, March 5, 2014

Patient Ratings & Comments

The Patient Rating score is an average of all responses to physician related questions on the national CG-CAHPS Medical Practice patient experience survey through Press Ganey. Responses are measured on a scale of 1 to 5, with 5 being the best score. Comments are also gathered from our CG-CAHPS Medical Practice Survey through Press Ganey and displayed in their entirety. Patients are de-identified for confidentiality and patient privacy.

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